Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4683525..4683875 Replicon chromosome
Accession NZ_CP059589
Organism Xanthomonas oryzae pv. oryzae strain IXO675

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO675_RS21800 Protein ID WP_011257368.1
Coordinates 4683525..4683659 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO675_RS21805 Protein ID WP_011407410.1
Coordinates 4683723..4683875 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO675_RS21785 (IXO675_021770) 4680539..4681483 - 945 WP_080493520.1 MBL fold metallo-hydrolase -
IXO675_RS21790 (IXO675_021775) 4681614..4682903 - 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO675_RS21795 (IXO675_021780) 4683072..4683281 - 210 WP_011407411.1 CsbD family protein -
IXO675_RS21800 (IXO675_021785) 4683525..4683659 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO675_RS21805 (IXO675_021790) 4683723..4683875 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO675_RS21810 (IXO675_021795) 4683983..4684906 - 924 WP_011407409.1 arginase -
IXO675_RS21815 4685228..4685446 + 219 Protein_4171 hypothetical protein -
IXO675_RS21820 (IXO675_021800) 4685438..4685902 + 465 Protein_4172 hypothetical protein -
IXO675_RS21825 4685899..4686441 + 543 Protein_4173 GTPase -
IXO675_RS21830 (IXO675_021815) 4686921..4687604 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T169040 WP_011257368.1 NZ_CP059589:c4683659-4683525 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T169040 NZ_CP076272:c3199960-3199625 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTATACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT169040 WP_011407410.1 NZ_CP059589:c4683875-4683723 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT169040 NZ_CP076272:c3200208-3199960 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References