Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 155784..156349 Replicon chromosome
Accession NZ_CP059589
Organism Xanthomonas oryzae pv. oryzae strain IXO675

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IXO675_RS00775 Protein ID WP_263132098.1
Coordinates 155784..156065 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A854CHP1
Locus tag IXO675_RS00780 Protein ID WP_011407243.1
Coordinates 156119..156349 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO675_RS00755 (IXO675_000745) 151967..152629 - 663 Protein_146 IS30 family transposase -
IXO675_RS00760 (IXO675_000750) 152634..153599 - 966 Protein_147 IS1595 family transposase -
IXO675_RS00765 (IXO675_000755) 153830..154081 - 252 WP_027703668.1 SymE family type I addiction module toxin -
IXO675_RS00770 (IXO675_000760) 154701..155669 + 969 WP_011258529.1 IS5-like element ISXo1 family transposase -
IXO675_RS00775 (IXO675_000765) 155784..156065 - 282 WP_263132098.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IXO675_RS00780 (IXO675_000770) 156119..156349 - 231 WP_011407243.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IXO675_RS00785 (IXO675_000775) 156416..157078 - 663 WP_011407244.1 hemolysin III family protein -
IXO675_RS00790 (IXO675_000780) 157256..159751 + 2496 WP_011407245.1 DEAD/DEAH box helicase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-78)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10866.75 Da        Isoelectric Point: 11.5917

>T169036 WP_263132098.1 NZ_CP059589:c156065-155784 [Xanthomonas oryzae pv. oryzae]
MEATADDIAIDNVPAAAALVKRVFAHVEQLIEPPDSGSRLQELKRSRYRQIVEPPCRVIYRLDGQRIVVVHVLRSERALR
KRRISRWKRLRKV

Download         Length: 282 bp

>T169036 NZ_CP076272:c2133922-2133819 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8452.69 Da        Isoelectric Point: 6.4625

>AT169036 WP_011407243.1 NZ_CP059589:c156349-156119 [Xanthomonas oryzae pv. oryzae]
MRTERVTTLKGQATELLAATERDKEPILITQHGLPSAYLVDVASYERMQQRMAILEGIARGEMAVAQGRTLTHEQA

Download         Length: 231 bp

>AT169036 NZ_CP076272:2133781-2134052 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A854CHP1

References