Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
| Location | 2837885..2838441 | Replicon | chromosome |
| Accession | NZ_CP059588 | ||
| Organism | Xanthomonas oryzae pv. oryzae strain IXO651 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | IXO651_RS13390 | Protein ID | WP_229002778.1 |
| Coordinates | 2837885..2838136 (-) | Length | 84 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A854CIX2 |
| Locus tag | IXO651_RS13395 | Protein ID | WP_011408759.1 |
| Coordinates | 2838163..2838441 (-) | Length | 93 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IXO651_RS13340 (IXO651_013330) | 2833991..2834307 | - | 317 | Protein_2552 | ATP-dependent DNA ligase | - |
| IXO651_RS13345 (IXO651_013340) | 2834589..2834765 | - | 177 | Protein_2553 | DUF3606 domain-containing protein | - |
| IXO651_RS13350 (IXO651_013345) | 2834987..2835388 | + | 402 | WP_011259345.1 | H-NS family nucleoid-associated regulatory protein | - |
| IXO651_RS13360 (IXO651_013355) | 2836331..2836332 | - | 2 | WP_094187731.1 | IS5 family transposase | - |
| IXO651_RS13365 (IXO651_013360) | 2836671..2836799 | - | 129 | WP_012444694.1 | hypothetical protein | - |
| IXO651_RS13370 | 2836768..2836887 | - | 120 | Protein_2557 | IS3 family transposase | - |
| IXO651_RS13375 (IXO651_013365) | 2837104..2837358 | - | 255 | WP_223293127.1 | hypothetical protein | - |
| IXO651_RS13380 (IXO651_013370) | 2837427..2837561 | - | 135 | WP_011051575.1 | hypothetical protein | - |
| IXO651_RS13385 | 2837554..2837808 | - | 255 | WP_198912806.1 | hypothetical protein | - |
| IXO651_RS13390 (IXO651_013375) | 2837885..2838136 | - | 252 | WP_229002778.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| IXO651_RS13395 (IXO651_013380) | 2838163..2838441 | - | 279 | WP_011408759.1 | CopG family ribbon-helix-helix protein | Antitoxin |
| IXO651_RS13400 (IXO651_013385) | 2838637..2839023 | - | 387 | WP_205421001.1 | hypothetical protein | - |
| IXO651_RS13405 (IXO651_013395) | 2839887..2841071 | - | 1185 | WP_011408397.1 | IS256-like element IS1113 family transposase | - |
| IXO651_RS13410 (IXO651_013400) | 2841652..2842617 | + | 966 | WP_109181928.1 | IS1595-like element ISXo5 family transposase | - |
| IXO651_RS13415 (IXO651_013405) | 2842767..2843324 | + | 558 | WP_011259349.1 | DNA-3-methyladenine glycosylase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | IScluster/Tn | - | - | 2835804..2842617 | 6813 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 84 a.a. Molecular weight: 9617.95 Da Isoelectric Point: 9.9718
>T169034 WP_229002778.1 NZ_CP059588:c2838136-2837885 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILALRHQKE
AGY
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILALRHQKE
AGY
Download Length: 252 bp
>T169034 NZ_CP076272:1668774-1668950 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA
Antitoxin
Download Length: 93 a.a. Molecular weight: 10826.11 Da Isoelectric Point: 4.9736
>AT169034 WP_011408759.1 NZ_CP059588:c2838441-2838163 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK
Download Length: 279 bp
>AT169034 NZ_CP076272:1668996-1669412 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
GCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCGTTACCTTCGCCATTAAATAGTCATGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAAGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCACCATGCGACAAAAATCGACGCCGTCCAGCTTGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
GCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCGTTACCTTCGCCATTAAATAGTCATGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAAGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCACCATGCGACAAAAATCGACGCCGTCCAGCTTGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|