Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 1767493..1769012 | Replicon | chromosome |
| Accession | NZ_CP059588 | ||
| Organism | Xanthomonas oryzae pv. oryzae strain IXO651 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | A0A0K0GMB6 |
| Locus tag | IXO651_RS08455 | Protein ID | WP_011259680.1 |
| Coordinates | 1768089..1769012 (+) | Length | 308 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | A0A0K0GMG7 |
| Locus tag | IXO651_RS08450 | Protein ID | WP_012445456.1 |
| Coordinates | 1767493..1768092 (+) | Length | 200 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IXO651_RS08420 | 1763220..1763594 | - | 375 | WP_229002607.1 | hypothetical protein | - |
| IXO651_RS08425 | 1763575..1763865 | - | 291 | WP_011409031.1 | hypothetical protein | - |
| IXO651_RS08430 (IXO651_008375) | 1764364..1765397 | + | 1034 | Protein_1610 | IS630 family transposase | - |
| IXO651_RS08435 (IXO651_008380) | 1765533..1766331 | + | 799 | WP_094187708.1 | IS5 family transposase | - |
| IXO651_RS08440 (IXO651_008385) | 1766318..1766806 | - | 489 | WP_027703988.1 | BrxE family protein | - |
| IXO651_RS08445 (IXO651_008390) | 1766838..1767128 | - | 291 | WP_229002604.1 | FaeA/PapI family transcriptional regulator | - |
| IXO651_RS08450 (IXO651_008395) | 1767493..1768092 | + | 600 | WP_012445456.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| IXO651_RS08455 (IXO651_008400) | 1768089..1769012 | + | 924 | WP_011259680.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| IXO651_RS08460 | 1769092..1769562 | - | 471 | WP_228329666.1 | helix-turn-helix domain-containing protein | - |
| IXO651_RS08465 (IXO651_008415) | 1770028..1770270 | + | 243 | WP_011259679.1 | hypothetical protein | - |
| IXO651_RS08470 (IXO651_008420) | 1770695..1771204 | + | 510 | WP_011259678.1 | hypothetical protein | - |
| IXO651_RS08475 (IXO651_008425) | 1771221..1771753 | - | 533 | Protein_1619 | protein N-lysine methyltransferase family protein | - |
| IXO651_RS08480 (IXO651_008430) | 1771773..1773149 | - | 1377 | WP_133264775.1 | IS5 family transposase | - |
| IXO651_RS08485 (IXO651_008435) | 1773261..1773413 | - | 153 | Protein_1621 | SAM-dependent methyltransferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 1771773..1773149 | 1376 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 308 a.a. Molecular weight: 34114.16 Da Isoelectric Point: 5.4588
>T169033 WP_011259680.1 NZ_CP059588:1768089-1769012 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA
Download Length: 924 bp
>T169033 NZ_CP076272:c1557670-1557476 [Escherichia coli]
TTGAGATATGACGATGTTAAACCATGTCCGTTTTGTGGTTGTCCATCAGTAACGGTGAAAGACATTTCAGGATATTACCG
GGCAAAATGCAACGGATGCGAATCCCGAACTGGCTATGGTGGAAGTGAAAAAGAAGCGCTCGAAAGATGGAATAAACGAA
CCACTGAAAATATTAATGGAGGCGTTCATGTATAA
TTGAGATATGACGATGTTAAACCATGTCCGTTTTGTGGTTGTCCATCAGTAACGGTGAAAGACATTTCAGGATATTACCG
GGCAAAATGCAACGGATGCGAATCCCGAACTGGCTATGGTGGAAGTGAAAAAGAAGCGCTCGAAAGATGGAATAAACGAA
CCACTGAAAATATTAATGGAGGCGTTCATGTATAA
Antitoxin
Download Length: 200 a.a. Molecular weight: 22051.76 Da Isoelectric Point: 10.1240
>AT169033 WP_012445456.1 NZ_CP059588:1767493-1768092 [Xanthomonas oryzae pv. oryzae]
MDTTIDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA
MDTTIDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA
Download Length: 600 bp
>AT169033 NZ_CP076272:1557299-1557477 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATTGTAGCGGTAATTTT
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATTGTAGCGGTAATTTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0K0GMB6 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0K0GMG7 |