169026

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 434308..434658 Replicon chromosome
Accession NZ_CP059587
Organism Xanthomonas oryzae pv. oryzae strain IXO644

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO644_RS02080 Protein ID WP_011257368.1
Coordinates 434524..434658 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO644_RS02075 Protein ID WP_011407410.1
Coordinates 434308..434460 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO644_RS02050 (IXO644_002040) 430579..431262 - 684 WP_011257363.1 dTMP kinase -
IXO644_RS02055 431742..432284 - 543 Protein_394 GTPase -
IXO644_RS02060 (IXO644_002055) 432281..432745 - 465 Protein_395 hypothetical protein -
IXO644_RS02065 432737..432955 - 219 Protein_396 hypothetical protein -
IXO644_RS02070 (IXO644_002060) 433277..434200 + 924 WP_011407409.1 arginase -
IXO644_RS02075 (IXO644_002065) 434308..434460 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO644_RS02080 (IXO644_002070) 434524..434658 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO644_RS02085 (IXO644_002075) 434902..435111 + 210 WP_011407411.1 CsbD family protein -
IXO644_RS02090 (IXO644_002080) 435280..436569 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO644_RS02095 (IXO644_002085) 436700..437644 + 945 WP_080496656.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T169026 WP_011257368.1 NZ_CP059587:434524-434658 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T169026 NZ_CP076271:100471-100887 [Escherichia coli]
GTGAACAAGACTTATATGCTTGATACCTGTATCTGCTCGTTCATCATGCGTGAACAGCCAGAAGCCGTCCTGAAGCGTCT
GGAGCAGGCGGTGCTACGCGGCCACCGTATAGTGGTCTCGGCCATCACCTACTCTGAAATGCGCTTCGGGGCTACCGGCC
CAAAGGCCTCACCACGTCACGTCCAACTGGTCGATGAATTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCC
GCAGTAGACGCCACCACGAAGATTAAAGTGGCACTGCGGCTGGCCGGGACGCCGATCGGCCCGAACGACACGGCGATTGC
CGGGCACGCCATCGCCGCCGGGGCGATACTGGTAACGAATAATACAAGAGAATTTGAGCGAGTGCCTGACTTGGTGCTGG
AAGACTGGGTGAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT169026 WP_011407410.1 NZ_CP059587:434308-434460 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT169026 NZ_CP076271:100244-100474 [Escherichia coli]
ATGAGAACCGTATCGATATTTAAAAATGGCAACAACCGCGCCATCCGTCTGCCTCGTGATCTGGATTTTGAGGGGGTGAG
CGAGCTCGAGATCGTCCGGGAAGGGGACAGCATCATCCTGCGCCCCGTCCGGCCAACCTGGGGATCATTCCTAGAGTACG
AAAAAGCCGATCCAGATTTTATGGCGGAGCGCGAGGATGTTGTCAGCGACGAAGGGCGATTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References