169023

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2063430..2063986 Replicon chromosome
Accession NZ_CP059586
Organism Xanthomonas oryzae pv. oryzae strain IXO639

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag IXO639_RS09595 Protein ID WP_229001948.1
Coordinates 2063735..2063986 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A854CIX2
Locus tag IXO639_RS09590 Protein ID WP_011408759.1
Coordinates 2063430..2063708 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO639_RS09570 (IXO639_009665) 2058547..2059104 - 558 WP_011259349.1 DNA-3-methyladenine glycosylase -
IXO639_RS09575 (IXO639_009670) 2059254..2060219 - 966 WP_109181928.1 IS1595-like element ISXo5 family transposase -
IXO639_RS09580 (IXO639_009675) 2060800..2061984 + 1185 WP_117231633.1 IS256 family transposase -
IXO639_RS09585 (IXO639_009685) 2062890..2063234 + 345 WP_198912817.1 hypothetical protein -
IXO639_RS09590 (IXO639_009690) 2063430..2063708 + 279 WP_011408759.1 CopG family ribbon-helix-helix protein Antitoxin
IXO639_RS09595 (IXO639_009695) 2063735..2063986 + 252 WP_229001948.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IXO639_RS09600 (IXO639_009700) 2064247..2064444 + 198 WP_004541336.1 hypothetical protein -
IXO639_RS09605 (IXO639_009705) 2064513..2064767 + 255 WP_223293127.1 hypothetical protein -
IXO639_RS09610 2064984..2065103 + 120 Protein_1840 IS3 family transposase -
IXO639_RS09615 2065072..2065200 + 129 WP_012444694.1 hypothetical protein -
IXO639_RS09625 (IXO639_009720) 2065631..2066032 - 402 WP_011259345.1 H-NS family nucleoid-associated regulatory protein -
IXO639_RS09630 (IXO639_009725) 2066254..2066430 + 177 Protein_1843 DUF3606 domain-containing protein -
IXO639_RS09635 (IXO639_009735) 2066712..2067049 + 338 Protein_1844 ATP-dependent DNA ligase -
IXO639_RS09640 (IXO639_009740) 2067125..2068216 - 1092 WP_041182166.1 ribonuclease D -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-81)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9603.92 Da        Isoelectric Point: 9.9718

>T169023 WP_229001948.1 NZ_CP059586:2063735-2063986 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Download         Length: 252 bp

>T169023 NZ_CP076271:c36751-36602 [Escherichia coli]
ATGACGAAATATGCCCTTATCGGGGTGCTCGCCGTGTGCGCCACGGTGTTGTGTTTTTTACTGATATTCAGGGAACGGTT
ATGTGAGCTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10826.11 Da        Isoelectric Point: 4.9736

>AT169023 WP_011408759.1 NZ_CP059586:2063430-2063708 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT169023 NZ_CP076271:36795-36856 [Escherichia coli]
TTAAGGTACTTCATGCAGGCCTCACGAGTTAATGGATTAACAAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A854CIX2

References