Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 427390..427740 Replicon chromosome
Accession NZ_CP059586
Organism Xanthomonas oryzae pv. oryzae strain IXO639

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO639_RS02010 Protein ID WP_011257368.1
Coordinates 427606..427740 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO639_RS02005 Protein ID WP_011407410.1
Coordinates 427390..427542 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO639_RS01980 (IXO639_001995) 423661..424344 - 684 WP_011257363.1 dTMP kinase -
IXO639_RS01985 424824..425366 - 543 Protein_380 GTPase -
IXO639_RS01990 (IXO639_002010) 425363..425827 - 465 Protein_381 hypothetical protein -
IXO639_RS01995 425819..426037 - 219 Protein_382 hypothetical protein -
IXO639_RS02000 (IXO639_002015) 426359..427282 + 924 WP_011407409.1 arginase -
IXO639_RS02005 (IXO639_002020) 427390..427542 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO639_RS02010 (IXO639_002025) 427606..427740 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO639_RS02015 (IXO639_002030) 427984..428193 + 210 WP_011407411.1 CsbD family protein -
IXO639_RS02020 (IXO639_002035) 428362..429651 + 1290 WP_075243865.1 tryptophan--tRNA ligase -
IXO639_RS02025 (IXO639_002040) 429782..430726 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T169021 WP_011257368.1 NZ_CP059586:427606-427740 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T169021 NZ_CP076270:4333538-4333849 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTTTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT169021 WP_011407410.1 NZ_CP059586:427390-427542 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT169021 NZ_CP076270:4333850-4334140 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References