Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 4922516..4924035 | Replicon | chromosome |
| Accession | NZ_CP059585 | ||
| Organism | Xanthomonas oryzae pv. oryzae strain IXO630 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | A0A0K0GMB6 |
| Locus tag | IXO630_RS23225 | Protein ID | WP_011259680.1 |
| Coordinates | 4923112..4924035 (+) | Length | 308 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | A0A0K0GMG7 |
| Locus tag | IXO630_RS23220 | Protein ID | WP_012445456.1 |
| Coordinates | 4922516..4923115 (+) | Length | 200 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IXO630_RS23190 (IXO630_023045) | 4918227..4919260 | + | 1034 | Protein_4434 | IS630 family transposase | - |
| IXO630_RS23195 (IXO630_023050) | 4919396..4919909 | + | 514 | Protein_4435 | IS5 family transposase | - |
| IXO630_RS23200 (IXO630_023055) | 4919982..4920950 | + | 969 | WP_011407175.1 | IS5-like element ISXo1 family transposase | - |
| IXO630_RS23205 (IXO630_023060) | 4921076..4921354 | + | 279 | Protein_4437 | transposase | - |
| IXO630_RS23210 (IXO630_023065) | 4921341..4921829 | - | 489 | WP_027703988.1 | BrxE family protein | - |
| IXO630_RS23215 (IXO630_023070) | 4921861..4922151 | - | 291 | WP_229002604.1 | FaeA/PapI family transcriptional regulator | - |
| IXO630_RS23220 (IXO630_023075) | 4922516..4923115 | + | 600 | WP_012445456.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| IXO630_RS23225 (IXO630_023080) | 4923112..4924035 | + | 924 | WP_011259680.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| IXO630_RS23230 | 4924115..4924585 | - | 471 | WP_228329666.1 | helix-turn-helix domain-containing protein | - |
| IXO630_RS23235 (IXO630_023095) | 4925051..4925293 | + | 243 | WP_011259679.1 | hypothetical protein | - |
| IXO630_RS23240 (IXO630_023100) | 4925718..4926227 | + | 510 | WP_011259678.1 | hypothetical protein | - |
| IXO630_RS23245 (IXO630_023105) | 4926244..4926776 | - | 533 | Protein_4445 | protein N-lysine methyltransferase family protein | - |
| IXO630_RS23250 (IXO630_023110) | 4926796..4928172 | - | 1377 | Protein_4446 | IS5 family transposase | - |
| IXO630_RS23255 (IXO630_023115) | 4928284..4928436 | - | 153 | Protein_4447 | SAM-dependent methyltransferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 308 a.a. Molecular weight: 34114.16 Da Isoelectric Point: 5.4588
>T169020 WP_011259680.1 NZ_CP059585:4923112-4924035 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA
Download Length: 924 bp
>T169020 NZ_CP076270:c3848844-3848569 [Escherichia coli]
ATGAGAACCAAGGTACAGGCTTTACGGAAGAAACAAAAAAATACATTGGATCAAATAGTTAAAACTCCTGTTCCTCAAGG
GATCAAGTGGTCTGATATAGAGTCACTGGTTAAAGCATTAGGCGGAGAAATTAAGGAAGGAAGAGGTTCGCGTTGCAAGT
TCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGTCGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTG
CGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA
ATGAGAACCAAGGTACAGGCTTTACGGAAGAAACAAAAAAATACATTGGATCAAATAGTTAAAACTCCTGTTCCTCAAGG
GATCAAGTGGTCTGATATAGAGTCACTGGTTAAAGCATTAGGCGGAGAAATTAAGGAAGGAAGAGGTTCGCGTTGCAAGT
TCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGTCGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTG
CGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA
Antitoxin
Download Length: 200 a.a. Molecular weight: 22051.76 Da Isoelectric Point: 10.1240
>AT169020 WP_012445456.1 NZ_CP059585:4922516-4923115 [Xanthomonas oryzae pv. oryzae]
MDTTIDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA
MDTTIDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA
Download Length: 600 bp
>AT169020 NZ_CP076270:c3848572-3848213 [Escherichia coli]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCAGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCAGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0K0GMB6 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0K0GMG7 |