169019

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3462580..3462930 Replicon chromosome
Accession NZ_CP059585
Organism Xanthomonas oryzae pv. oryzae strain IXO630

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO630_RS16075 Protein ID WP_011257368.1
Coordinates 3462796..3462930 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO630_RS16070 Protein ID WP_011407410.1
Coordinates 3462580..3462732 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO630_RS16045 (IXO630_015935) 3458851..3459534 - 684 WP_011257363.1 dTMP kinase -
IXO630_RS16050 3460014..3460556 - 543 Protein_3086 GTPase -
IXO630_RS16055 (IXO630_015950) 3460553..3461017 - 465 Protein_3087 hypothetical protein -
IXO630_RS16060 3461009..3461227 - 219 Protein_3088 hypothetical protein -
IXO630_RS16065 (IXO630_015955) 3461549..3462472 + 924 WP_011407409.1 arginase -
IXO630_RS16070 (IXO630_015960) 3462580..3462732 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO630_RS16075 (IXO630_015965) 3462796..3462930 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO630_RS16080 (IXO630_015970) 3463174..3463383 + 210 WP_011407411.1 CsbD family protein -
IXO630_RS16085 (IXO630_015975) 3463552..3464841 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO630_RS16090 (IXO630_015980) 3464972..3465916 + 945 WP_041181936.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T169019 WP_011257368.1 NZ_CP059585:3462796-3462930 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T169019 NZ_CP076270:3523756-3524220 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTACGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT169019 WP_011407410.1 NZ_CP059585:3462580-3462732 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT169019 NZ_CP076270:3523421-3523756 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTCTTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References