169013

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 420664..421014 Replicon chromosome
Accession NZ_CP059584
Organism Xanthomonas oryzae pv. oryzae strain IXO493

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO493_RS01975 Protein ID WP_011257368.1
Coordinates 420880..421014 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO493_RS01970 Protein ID WP_011407410.1
Coordinates 420664..420816 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO493_RS01945 (IXO493_001935) 416935..417618 - 684 WP_011257363.1 dTMP kinase -
IXO493_RS01950 418098..418640 - 543 Protein_373 GTPase -
IXO493_RS01955 (IXO493_001950) 418637..419101 - 465 Protein_374 hypothetical protein -
IXO493_RS01960 419093..419311 - 219 Protein_375 hypothetical protein -
IXO493_RS01965 (IXO493_001955) 419633..420556 + 924 WP_011407409.1 arginase -
IXO493_RS01970 (IXO493_001960) 420664..420816 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO493_RS01975 (IXO493_001965) 420880..421014 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO493_RS01980 (IXO493_001970) 421258..421467 + 210 WP_011407411.1 CsbD family protein -
IXO493_RS01985 (IXO493_001975) 421636..422925 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO493_RS01990 (IXO493_001980) 423056..424000 + 945 WP_041181936.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T169013 WP_011257368.1 NZ_CP059584:420880-421014 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T169013 NZ_CP076270:c2265701-2265447 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGACGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT169013 WP_011407410.1 NZ_CP059584:420664-420816 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT169013 NZ_CP076270:c2265949-2265698 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATCATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References