Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 3070484..3071040 Replicon chromosome
Accession NZ_CP059583
Organism Xanthomonas oryzae pv. oryzae strain IXO365

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag IXO365_RS14475 Protein ID WP_229001948.1
Coordinates 3070484..3070735 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A854CIX2
Locus tag IXO365_RS14480 Protein ID WP_011408759.1
Coordinates 3070762..3071040 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO365_RS14425 (IXO365_014435) 3066254..3067345 + 1092 WP_075239568.1 ribonuclease D -
IXO365_RS14430 (IXO365_014440) 3067442..3067758 - 317 Protein_2746 ATP-dependent DNA ligase -
IXO365_RS14435 (IXO365_014450) 3068040..3068216 - 177 Protein_2747 DUF3606 domain-containing protein -
IXO365_RS14440 (IXO365_014455) 3068438..3068839 + 402 WP_011259345.1 H-NS family nucleoid-associated regulatory protein -
IXO365_RS14450 3069270..3069398 - 129 WP_012444694.1 hypothetical protein -
IXO365_RS14455 3069367..3069486 - 120 Protein_2750 IS3 family transposase -
IXO365_RS14460 (IXO365_014470) 3069703..3069957 - 255 WP_223293127.1 hypothetical protein -
IXO365_RS14465 3070026..3070160 - 135 WP_011051575.1 hypothetical protein -
IXO365_RS14470 (IXO365_014475) 3070153..3070407 - 255 WP_198912806.1 hypothetical protein -
IXO365_RS14475 (IXO365_014480) 3070484..3070735 - 252 WP_229001948.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IXO365_RS14480 (IXO365_014485) 3070762..3071040 - 279 WP_011408759.1 CopG family ribbon-helix-helix protein Antitoxin
IXO365_RS14485 (IXO365_014490) 3071236..3071580 - 345 WP_199285675.1 hypothetical protein -
IXO365_RS14490 (IXO365_014500) 3072057..3073292 + 1236 WP_012443979.1 ISL3-like element ISXoo13 family transposase -
IXO365_RS14495 (IXO365_014505) 3073621..3074856 - 1236 WP_044756360.1 ISL3-like element ISXoo13 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-81)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9603.92 Da        Isoelectric Point: 9.9718

>T169011 WP_229001948.1 NZ_CP059583:c3070735-3070484 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Download         Length: 252 bp

>T169011 NZ_CP076270:c1681503-1680181 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CAGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTAACGTCATTACCCGAAAA
TGAAACCATAACGCGCCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGGCTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCTCTGGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCGCAGGAGAAGACAGCGCTG
CTTAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCTGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCGTTTTTGATGGGGTCCAGCGAGGCGCTTCGCGATCGTTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGATGGACATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTAAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10826.11 Da        Isoelectric Point: 4.9736

>AT169011 WP_011408759.1 NZ_CP059583:c3071040-3070762 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT169011 NZ_CP076270:c1681769-1681503 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACACTATGCGACACGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A854CIX2

References