Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1880423..1881942 Replicon chromosome
Accession NZ_CP059583
Organism Xanthomonas oryzae pv. oryzae strain IXO365

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag IXO365_RS09120 Protein ID WP_011259680.1
Coordinates 1881019..1881942 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A0K0GMG7
Locus tag IXO365_RS09115 Protein ID WP_012445456.1
Coordinates 1880423..1881022 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO365_RS09085 (IXO365_009060) 1876134..1877167 + 1034 Protein_1720 IS630 family transposase -
IXO365_RS09090 (IXO365_009065) 1877303..1877816 + 514 Protein_1721 IS5 family transposase -
IXO365_RS09095 (IXO365_009070) 1877889..1878857 + 969 WP_011258529.1 IS5-like element ISXo1 family transposase -
IXO365_RS09100 (IXO365_009075) 1878983..1879261 + 279 Protein_1723 transposase -
IXO365_RS09105 (IXO365_009080) 1879248..1879736 - 489 WP_027703988.1 BrxE family protein -
IXO365_RS09110 (IXO365_009085) 1879768..1880058 - 291 WP_229002604.1 FaeA/PapI family transcriptional regulator -
IXO365_RS09115 (IXO365_009090) 1880423..1881022 + 600 WP_012445456.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
IXO365_RS09120 (IXO365_009095) 1881019..1881942 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IXO365_RS09125 1882022..1882492 - 471 WP_228329666.1 helix-turn-helix domain-containing protein -
IXO365_RS09130 (IXO365_009110) 1882958..1883200 + 243 WP_011259679.1 hypothetical protein -
IXO365_RS09135 (IXO365_009115) 1883625..1884134 + 510 WP_011259678.1 hypothetical protein -
IXO365_RS09140 (IXO365_009120) 1884151..1884683 - 533 Protein_1731 protein N-lysine methyltransferase family protein -
IXO365_RS09145 (IXO365_009125) 1884703..1886079 - 1377 Protein_1732 IS5 family transposase -
IXO365_RS09150 (IXO365_009130) 1886191..1886343 - 153 Protein_1733 SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T169010 WP_011259680.1 NZ_CP059583:1881019-1881942 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T169010 NZ_CP076270:1589369-1589545 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22051.76 Da        Isoelectric Point: 10.1240

>AT169010 WP_012445456.1 NZ_CP059583:1880423-1881022 [Xanthomonas oryzae pv. oryzae]
MDTTIDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT169010 NZ_CP076270:1589591-1590007 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
GCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCGTTACCTTCGCCATTAAATAGTCATGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAAGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCACCATGCGACAAAAATCGACGCCGTCCAGCTTGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A0K0GMG7

References