169009

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 420672..421022 Replicon chromosome
Accession NZ_CP059583
Organism Xanthomonas oryzae pv. oryzae strain IXO365

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO365_RS01975 Protein ID WP_011257368.1
Coordinates 420888..421022 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO365_RS01970 Protein ID WP_011407410.1
Coordinates 420672..420824 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO365_RS01945 (IXO365_001945) 416943..417626 - 684 WP_011257363.1 dTMP kinase -
IXO365_RS01950 418106..418648 - 543 Protein_373 GTPase -
IXO365_RS01955 (IXO365_001960) 418645..419109 - 465 Protein_374 hypothetical protein -
IXO365_RS01960 419101..419319 - 219 Protein_375 hypothetical protein -
IXO365_RS01965 (IXO365_001965) 419641..420564 + 924 WP_011407409.1 arginase -
IXO365_RS01970 (IXO365_001970) 420672..420824 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO365_RS01975 (IXO365_001975) 420888..421022 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO365_RS01980 (IXO365_001980) 421266..421475 + 210 WP_011407411.1 CsbD family protein -
IXO365_RS01985 (IXO365_001985) 421644..422933 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO365_RS01990 (IXO365_001990) 423064..424008 + 945 WP_041181936.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T169009 WP_011257368.1 NZ_CP059583:420888-421022 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T169009 NZ_CP076270:c1478522-1478328 [Escherichia coli]
TTGAGATATGACGATGTTAAACCATGTCCGTTTTGTGGTTGTCCATCAGTAACGGTGAAAGACATTTCAGGATATTACCG
GGCAAAATGCAACGGATGCGAATCCCGAACTGGCTATGGTGGAAGTGAAAAAGAAGCGCTCGAAAGATGGAATAAACGAA
CCACTGAAAATATTAATGGAGGCGTTCATGTATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT169009 WP_011407410.1 NZ_CP059583:420672-420824 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT169009 NZ_CP076270:1478151-1478329 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATTGTAGCGGTAATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References