169006

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2102312..2102868 Replicon chromosome
Accession NZ_CP059582
Organism Xanthomonas oryzae pv. oryzae strain IXO220

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag IXO220_RS09860 Protein ID WP_229001948.1
Coordinates 2102617..2102868 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A854CIX2
Locus tag IXO220_RS09855 Protein ID WP_011408759.1
Coordinates 2102312..2102590 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO220_RS09835 (IXO220_009920) 2097429..2097986 - 558 WP_011259349.1 DNA-3-methyladenine glycosylase -
IXO220_RS09840 (IXO220_009925) 2098136..2099101 - 966 WP_109181970.1 IS1595-like element ISXo5 family transposase -
IXO220_RS09845 (IXO220_009930) 2099682..2100866 + 1185 WP_117231633.1 IS256 family transposase -
IXO220_RS09850 (IXO220_009940) 2101730..2102116 + 387 WP_205421001.1 hypothetical protein -
IXO220_RS09855 (IXO220_009945) 2102312..2102590 + 279 WP_011408759.1 CopG family ribbon-helix-helix protein Antitoxin
IXO220_RS09860 (IXO220_009950) 2102617..2102868 + 252 WP_229001948.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IXO220_RS09865 (IXO220_009955) 2102945..2103199 + 255 WP_198912806.1 hypothetical protein -
IXO220_RS09870 2103192..2103326 + 135 WP_011051575.1 hypothetical protein -
IXO220_RS09875 (IXO220_009960) 2103395..2103649 + 255 WP_223293127.1 hypothetical protein -
IXO220_RS09880 2103866..2103985 + 120 Protein_1894 IS3 family transposase -
IXO220_RS09890 (IXO220_009975) 2104513..2104914 - 402 WP_011259345.1 H-NS family nucleoid-associated regulatory protein -
IXO220_RS09895 (IXO220_009980) 2105136..2105312 + 177 Protein_1896 DUF3606 domain-containing protein -
IXO220_RS09900 (IXO220_009990) 2105594..2105931 + 338 Protein_1897 ATP-dependent DNA ligase -
IXO220_RS09905 (IXO220_009995) 2106007..2107098 - 1092 WP_041182166.1 ribonuclease D -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-81)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9603.92 Da        Isoelectric Point: 9.9718

>T169006 WP_229001948.1 NZ_CP059582:2102617-2102868 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Download         Length: 252 bp

>T169006 NZ_CP076270:c1337230-1337123 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10826.11 Da        Isoelectric Point: 4.9736

>AT169006 WP_011408759.1 NZ_CP059582:2102312-2102590 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT169006 NZ_CP076270:1337278-1337344 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTAAACCTCTCAACGTGCGGGGGGTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A854CIX2

References