Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1577516..1579035 Replicon chromosome
Accession NZ_CP059582
Organism Xanthomonas oryzae pv. oryzae strain IXO220

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag IXO220_RS07590 Protein ID WP_011259680.1
Coordinates 1578112..1579035 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag IXO220_RS07585 Protein ID WP_011409027.1
Coordinates 1577516..1578115 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO220_RS07550 (IXO220_007580) 1573184..1573720 - 537 WP_024743012.1 lipocalin family protein -
IXO220_RS07560 1574097..1574471 - 375 WP_237384745.1 hypothetical protein -
IXO220_RS07565 1574452..1574742 - 291 WP_011409031.1 hypothetical protein -
IXO220_RS07570 (IXO220_007600) 1575241..1576272 + 1032 WP_151421460.1 IS630 family transposase -
IXO220_RS07575 (IXO220_007605) 1576254..1576829 - 576 WP_080493559.1 BrxE family protein -
IXO220_RS07580 (IXO220_007610) 1576861..1577151 - 291 WP_233282844.1 FaeA/PapI family transcriptional regulator -
IXO220_RS07585 (IXO220_007615) 1577516..1578115 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
IXO220_RS07590 (IXO220_007620) 1578112..1579035 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IXO220_RS07595 1579115..1579585 - 471 WP_228329666.1 helix-turn-helix domain-containing protein -
IXO220_RS07600 (IXO220_007635) 1580051..1580293 + 243 WP_011259679.1 hypothetical protein -
IXO220_RS07605 (IXO220_007640) 1580718..1581227 + 510 WP_011259678.1 hypothetical protein -
IXO220_RS07610 (IXO220_007645) 1581244..1581776 - 533 Protein_1453 protein N-lysine methyltransferase family protein -
IXO220_RS07615 (IXO220_007650) 1581796..1583172 - 1377 Protein_1454 IS5 family transposase -
IXO220_RS07620 (IXO220_007655) 1583284..1583436 - 153 Protein_1455 SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T169005 WP_011259680.1 NZ_CP059582:1578112-1579035 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T169005 NZ_CP076270:c531200-530982 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT169005 WP_011409027.1 NZ_CP059582:1577516-1578115 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT169005 NZ_CP076270:c531600-531226 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References