169004

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 427374..427724 Replicon chromosome
Accession NZ_CP059582
Organism Xanthomonas oryzae pv. oryzae strain IXO220

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO220_RS02010 Protein ID WP_011257368.1
Coordinates 427590..427724 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO220_RS02005 Protein ID WP_011407410.1
Coordinates 427374..427526 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO220_RS01980 (IXO220_001995) 423645..424328 - 684 WP_011257363.1 dTMP kinase -
IXO220_RS01985 424808..425350 - 543 Protein_380 GTPase -
IXO220_RS01990 (IXO220_002010) 425347..425811 - 465 Protein_381 hypothetical protein -
IXO220_RS01995 425803..426021 - 219 Protein_382 hypothetical protein -
IXO220_RS02000 (IXO220_002015) 426343..427266 + 924 WP_011407409.1 arginase -
IXO220_RS02005 (IXO220_002020) 427374..427526 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO220_RS02010 (IXO220_002025) 427590..427724 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO220_RS02015 (IXO220_002030) 427968..428177 + 210 WP_011407411.1 CsbD family protein -
IXO220_RS02020 (IXO220_002035) 428346..429635 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO220_RS02025 (IXO220_002040) 429766..430710 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T169004 WP_011257368.1 NZ_CP059582:427590-427724 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T169004 NZ_CP076270:c277297-277019 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATGCTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT169004 WP_011407410.1 NZ_CP059582:427374-427526 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT169004 NZ_CP076270:c277560-277300 [Escherichia coli]
ATGGCTGCTAACGCATTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References