169001

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2807772..2808122 Replicon chromosome
Accession NZ_CP059581
Organism Xanthomonas oryzae pv. oryzae strain IXO98

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO98_RS13065 Protein ID WP_011257368.1
Coordinates 2807988..2808122 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO98_RS13060 Protein ID WP_011407410.1
Coordinates 2807772..2807924 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO98_RS13035 (IXO98_012960) 2804043..2804726 - 684 WP_011257363.1 dTMP kinase -
IXO98_RS13040 2805206..2805748 - 543 Protein_2491 GTPase -
IXO98_RS13045 (IXO98_012975) 2805745..2806209 - 465 Protein_2492 hypothetical protein -
IXO98_RS13050 2806201..2806419 - 219 Protein_2493 hypothetical protein -
IXO98_RS13055 (IXO98_012980) 2806741..2807664 + 924 WP_011407409.1 arginase -
IXO98_RS13060 (IXO98_012985) 2807772..2807924 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO98_RS13065 (IXO98_012990) 2807988..2808122 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO98_RS13070 (IXO98_012995) 2808366..2808575 + 210 WP_011407411.1 CsbD family protein -
IXO98_RS13075 (IXO98_013000) 2808744..2810033 + 1290 WP_075243865.1 tryptophan--tRNA ligase -
IXO98_RS13080 (IXO98_013005) 2810164..2811108 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T169001 WP_011257368.1 NZ_CP059581:2807988-2808122 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T169001 NZ_CP076269:c43678-43280 [Escherichia coli]
ATGCTGAAGTTTATGCTCGATACCAACATCTGCATTTTTACGATAAAGAACAAACCCGCCAGTGTCAGGGAACGTTTTAA
CCTGAACCAGGGGAGAATGTGCATCAGTTCGGTCACTCTGATGGAGCTGATATATGGTGCAGAAAAAAGCCAGATGCCTG
AACGTAATCTCGCTGTGATCGAGGGATTTGTTTCCCGCATTGATGTTCTGGATTACGACGCTGCCGCAGCCACACACAGC
GGCCAGATAAGAGCAGAACTTGCCCGTCAGGGACGCCCTGTCGGGCCATTTGATCAAATGATCGCAGGTCATGCCCGCAG
TCGGGGACTGATTATTGTGACTAATAACACCCGGGAATTTGAACGTGTGGACGGTCTGAGAATTGAAGACTGGAGCTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT169001 WP_011407410.1 NZ_CP059581:2807772-2807924 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT169001 NZ_CP076269:c43905-43678 [Escherichia coli]
ATGGAAACCACCGTATTTCTCAGCAACCGCAGCCAGGCGGTCAGACTGCCAAAAGCGGTTGCATTGCCGGAAAACGTAAA
ACGCGTTGAAGTGATTGCTGTCGGACGAACCCGAATCATTACGCCTGCCGGAGAGACATGGGACGAATGGTTCGACGGAA
ACAGTGTCAGCGCTGATTTTATGGATAACAGGGAACAGCCTGGTATGCAGGAAAGGGAGTCATTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References