Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 1319782..1320293 Replicon chromosome
Accession NZ_CP059564
Organism Alysiella filiformis strain DSM 16848

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H3L97_RS06520 Protein ID WP_097113562.1
Coordinates 1319782..1320042 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag H3L97_RS06525 Protein ID WP_097113561.1
Coordinates 1320039..1320293 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H3L97_RS06500 1315646..1316935 + 1290 WP_097113566.1 FAD-dependent oxidoreductase -
H3L97_RS06505 1317038..1318225 - 1188 WP_097113565.1 divalent metal cation transporter -
H3L97_RS06510 1318354..1318833 - 480 WP_097113564.1 hypothetical protein -
H3L97_RS06515 1318872..1319609 - 738 WP_097113563.1 5-oxoprolinase subunit PxpA -
H3L97_RS06520 1319782..1320042 - 261 WP_097113562.1 Txe/YoeB family addiction module toxin Toxin
H3L97_RS06525 1320039..1320293 - 255 WP_097113561.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
H3L97_RS06530 1320374..1320913 - 540 WP_097113560.1 hypothetical protein -
H3L97_RS06535 1320933..1321658 - 726 WP_097113559.1 hypothetical protein -
H3L97_RS06540 1321671..1322600 - 930 WP_097113558.1 biotin-dependent carboxyltransferase family protein -
H3L97_RS06545 1322818..1323462 - 645 WP_097113557.1 5-oxoprolinase subunit PxpB -
H3L97_RS06550 1323636..1325072 - 1437 WP_097113668.1 NAD-dependent succinate-semialdehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10398.90 Da        Isoelectric Point: 6.7172

>T168974 WP_097113562.1 NZ_CP059564:c1320042-1319782 [Alysiella filiformis]
MKLIFAETAWQDYVYWQTADRKILKRINLLIQDIQREPFDGIGKPEPLRFHLSGFWSRRIDEEHRLIYAIENESVLIASC
RYHYGE

Download         Length: 261 bp

>T168974 NZ_CP076264:c3871705-3871475 [Escherichia coli]
CTGGATCAGCTATTTAAATCACCTTTACCTCAAGGAATCAAATGGACTGATATAGAATCTCTGGTTAAAGCGTTAGGCGG
AGAAATTAAGGAAGGTAGGGGGTCGCGCTGTAAGTTCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGT
CGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTGCGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9684.94 Da        Isoelectric Point: 6.7158

>AT168974 WP_097113561.1 NZ_CP059564:c1320293-1320039 [Alysiella filiformis]
MHTLSYSEARQNLAKTMQEVVQNHEPVLITRTKNNEDCVLMSLAHYRSLEETAYLLRSPVNAQRLNQAIQQLKNGNGMER
ELSE

Download         Length: 255 bp

>AT168974 NZ_CP076264:c3871478-3871119 [Escherichia coli]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCTGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References