Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RelE(toxin)
Location 856583..857018 Replicon chromosome
Accession NZ_CP059564
Organism Alysiella filiformis strain DSM 16848

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H3L97_RS04200 Protein ID WP_182073094.1
Coordinates 856746..857018 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H3L97_RS04195 Protein ID WP_097113956.1
Coordinates 856583..856756 (+) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H3L97_RS04175 852906..853142 - 237 WP_097113898.1 acyl carrier protein -
H3L97_RS04180 853312..853581 - 270 WP_097113899.1 oxidative damage protection protein -
H3L97_RS04185 853650..854618 - 969 WP_143269111.1 sel1 repeat family protein -
H3L97_RS04190 854773..856263 + 1491 WP_097113901.1 Do family serine endopeptidase -
H3L97_RS04195 856583..856756 + 174 WP_097113956.1 stability determinant Antitoxin
H3L97_RS04200 856746..857018 + 273 WP_182073094.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H3L97_RS04210 857320..857970 - 651 WP_097113903.1 MBL fold metallo-hydrolase -
H3L97_RS04215 858310..859980 - 1671 WP_097113904.1 formate--tetrahydrofolate ligase -
H3L97_RS04220 860149..861558 - 1410 WP_097113905.1 cysteine--tRNA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10265.85 Da        Isoelectric Point: 4.7318

>T168973 WP_182073094.1 NZ_CP059564:856746-857018 [Alysiella filiformis]
MLVNWSDEANADLNEIVDFICLDNPLAAIDLSELLFETAEKIGNMPYMGKNGRVSGTREFVAHPKYVLVYQVQLNEILIL
RVLHTSRKYP

Download         Length: 273 bp

>T168973 NZ_CP076264:c3850139-3849612 [Escherichia coli]
ATGGATGATCTGACGATAGAGATTCTGACCGATGATGCAGATTATGATCTACAGCGATTCGACTGCGGCGAGGAAGCGTT
AAATCTCTTTCTGACGACACATCTCGTTCGTCAACATCGCAACAAAATTCTGCGAGCGTATATCCTTTGTCGCAACACTC
CAGAACGTCAGGTGCTGGGATATTACACATTATGCGGCAGTTGTTTTGAACGAGCCGCATTGCCCTCGAAATCGAAACAG
AAAAAAATTCCCTACAAAAATATTCCCAGCGTTACTCTTGGGCGTCTGGCAATTGATCGTTCATTACAGGGGCAGGGATG
GGGAGCAACACTGGTTGCTCATGCCATGAAAGTCGTCTGGTCAGCCTCTTTAGCGGTAGGTATTCACGGTCTTTTTGTCG
AGGCGCTGAATAAAAAAGCCCATACGTTTTATCAATCGCTGGGCTTTATCCCGTTGGTCGGAGAAAACGAAAATGCGTTA
TTTTTCCCAACCAAATCCATCGAACTGCTTTTCACACAGAGCGATTAA

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6541.35 Da        Isoelectric Point: 6.0577

>AT168973 WP_097113956.1 NZ_CP059564:856583-856756 [Alysiella filiformis]
IIELLTHQFFDTEEADYDAWFREKVEAALHSTKPAIPHDEVVARVRHKLAARVQNAG

Download         Length: 174 bp

>AT168973 NZ_CP076264:c3850412-3850146 [Escherichia coli]
ATGTCTGCTGTTAAAAAGCAGCGTATCGATCTGCGTTTAACTGACGATGACAAAAGTATGATTGAGGAAGCGGCAGCGAT
ATCTAATCAGTCCGTCAGCCAATTTATGTTGAACAGCGCTTCGCAGCGGGCTGCGGAAGTGATTGAACAGCATCGGCGGG
TGATCCTCAATGAGGAATCCTGGACGCGGGTGATGGATGCGCTGAGTAATCCACCGTCACCTGGTGAAAAGCTAAAACGT
GCGGCAAAACGTCTTCAGGGAATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References