Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 162755..163262 Replicon chromosome
Accession NZ_CP059564
Organism Alysiella filiformis strain DSM 16848

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag H3L97_RS00950 Protein ID WP_097113728.1
Coordinates 162996..163262 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag H3L97_RS00945 Protein ID WP_097113727.1
Coordinates 162755..163009 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H3L97_RS00910 158082..159137 - 1056 WP_097113720.1 metallophosphoesterase -
H3L97_RS00915 159219..159827 - 609 WP_097113721.1 DUF4230 domain-containing protein -
H3L97_RS00920 160311..160985 - 675 WP_097113723.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
H3L97_RS00925 161133..161429 - 297 WP_097113724.1 BrnA antitoxin family protein -
H3L97_RS00930 161416..161697 - 282 WP_097113825.1 BrnT family toxin -
H3L97_RS00935 161792..162238 - 447 WP_143269103.1 hypothetical protein -
H3L97_RS00940 162268..162741 - 474 WP_097113726.1 preQ(1) synthase -
H3L97_RS00945 162755..163009 - 255 WP_097113727.1 CopG family transcriptional regulator Antitoxin
H3L97_RS00950 162996..163262 - 267 WP_097113728.1 BrnT family toxin Toxin
H3L97_RS00955 163349..163951 - 603 WP_097113729.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
H3L97_RS00960 163956..164483 - 528 WP_097113826.1 disulfide bond formation protein B -
H3L97_RS00965 164691..164909 + 219 WP_179655782.1 NF038104 family lipoprotein -
H3L97_RS00970 164902..165567 + 666 WP_097113732.1 7-cyano-7-deazaguanine synthase QueC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin

CopG antitoxin

(16-75)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10519.91 Da        Isoelectric Point: 7.5211

>T168972 WP_097113728.1 NZ_CP059564:c163262-162996 [Alysiella filiformis]
MFEFEYDPNKSQSNHTKHGIDFETAQYLWQDPQLLSIPIQTEPEIRHLAIGIIGEKHWSAIYTHRNGKIRLISVRRSRDK
EKMLYETH

Download         Length: 267 bp

>T168972 NZ_CP076264:3543050-3543514 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTTTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9904.28 Da        Isoelectric Point: 5.0623

>AT168972 WP_097113727.1 NZ_CP059564:c163009-162755 [Alysiella filiformis]
MKPIDTEVFERKFDDNQEDILEYLDLSQATRVHQNKIATRRVNVDFPLWMLESLDREAANLGVARQALIKMWLSQHLPPN
QQNI

Download         Length: 255 bp

>AT168972 NZ_CP076264:3542715-3543050 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTCTTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References