Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 241098..242775 Replicon chromosome
Accession NZ_CP059560
Organism Aromatoleum petrolei strain ToN1

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag ToN1_RS01055 Protein ID WP_169206412.1
Coordinates 241918..242775 (-) Length 286 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag ToN1_RS01050 Protein ID WP_169206411.1
Coordinates 241098..241925 (-) Length 276 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ToN1_RS01030 (ToN1_02120) 236277..237779 - 1503 WP_169206408.1 aldehyde dehydrogenase -
ToN1_RS01035 (ToN1_02130) 237788..238612 - 825 WP_210147955.1 aspartate dehydrogenase -
ToN1_RS01040 (ToN1_02140) 238609..240294 - 1686 WP_169206409.1 thiamine pyrophosphate-binding protein -
ToN1_RS01045 (ToN1_02150) 240284..241084 - 801 WP_169206410.1 SDR family oxidoreductase -
ToN1_RS01050 (ToN1_02160) 241098..241925 - 828 WP_169206411.1 IclR family transcriptional regulator Antitoxin
ToN1_RS01055 (ToN1_02170) 241918..242775 - 858 WP_169206412.1 alpha/beta hydrolase Toxin
ToN1_RS01060 (ToN1_02180) 242791..243546 - 756 WP_210147956.1 SDR family oxidoreductase -
ToN1_RS01065 (ToN1_02190) 243558..244331 - 774 WP_169206414.1 ABC transporter permease -
ToN1_RS01070 (ToN1_02200) 244351..245343 - 993 WP_169206415.1 ABC transporter substrate-binding protein -
ToN1_RS01075 (ToN1_02210) 245397..246266 - 870 WP_210147957.1 ABC transporter ATP-binding protein -
ToN1_RS01080 (ToN1_02220) 246397..247260 - 864 WP_169206416.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(39-268)

Antitoxin

Transcription regulator IclR, N-terminal

(18-67)


Sequences

Toxin        


Download         Length: 286 a.a.        Molecular weight: 29783.99 Da        Isoelectric Point: 6.4825

>T168967 WP_169206412.1 NZ_CP059560:c242775-241918 [Aromatoleum petrolei]
MRTHEERLAALGTHFPLVEAGEGGRRWTYRTAGRGGRTLVLLHGIGSSSASWLDVALAAGRDFRVVAWDAPGYGGSTPLA
AERPLATDYAQSLEGFLATLGIEGCVLVGHSLGALMATAYAAAYPRGRAAQLILVSPARGYGAREFDAERERVRASRLQA
LAALGVAGMAAERAGRLVSPSAGASVREWVRWNMASLNADGYRQATELLCGDDLARYAPAPLPVACFCGADDVVTPPAAC
EAVAAAYGVPLVLLPGCGHASPVEIPHLLAATLRESIEMKGECCE

Download         Length: 858 bp

>T168967 NZ_CP076264:c2237441-2237187 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin


Download         Length: 276 a.a.        Molecular weight: 30032.32 Da        Isoelectric Point: 5.9732

>AT168967 WP_169206411.1 NZ_CP059560:c241925-241098 [Aromatoleum petrolei]
VSDDNSLDHPGNKYSVPALERGLRLLGEFSRHDPVLSAAELARRLDLPRSTVFRMLTTLEDLGFVERAEGGRDFRLGIAV
LRLGFEYLSSLELTELGMPILGRLRDEIGYASNLVVRDGRSIVYVAKVTPASWIASSVTVGTRLPAHATVFGRILLAELS
LDDLRALYPEEHLERHSGQTPATAMDLFNLLQLDKGRDCIVGEGFFEPSISTVAAPVRDREGQVIAALGATVPFGQIEEG
LRESLVTHIRAAALELSSALGYSQRRARTGKVISL

Download         Length: 828 bp

>AT168967 NZ_CP076264:c2237689-2237438 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References