Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 1170526..1171167 Replicon chromosome
Accession NZ_CP059479
Organism Acinetobacter baumannii strain 17-84

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag H2Q98_RS06200 Protein ID WP_016802636.1
Coordinates 1170778..1171167 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID F0KQ03
Locus tag H2Q98_RS06195 Protein ID WP_014207740.1
Coordinates 1170526..1170771 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H2Q98_RS06175 1166027..1167034 + 1008 WP_002116730.1 DNA-directed RNA polymerase subunit alpha -
H2Q98_RS06180 1167053..1167430 + 378 WP_002049717.1 50S ribosomal protein L17 -
H2Q98_RS06185 1167612..1169102 + 1491 WP_002116796.1 NAD(P)/FAD-dependent oxidoreductase -
H2Q98_RS06190 1169153..1170325 - 1173 WP_002116790.1 acyl-CoA dehydrogenase family protein -
H2Q98_RS06195 1170526..1170771 + 246 WP_014207740.1 succinate dehydrogenase assembly factor 2 Antitoxin
H2Q98_RS06200 1170778..1171167 + 390 WP_016802636.1 hypothetical protein Toxin
H2Q98_RS06205 1171938..1173026 + 1089 WP_002116869.1 hypothetical protein -
H2Q98_RS06210 1173111..1173686 + 576 WP_005078319.1 rhombosortase -
H2Q98_RS06215 1173866..1176076 + 2211 WP_002116854.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(6-78)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15475.66 Da        Isoelectric Point: 7.9230

>T168902 WP_016802636.1 NZ_CP059479:1170778-1171167 [Acinetobacter baumannii]
MIKELNFELKYSLVSVIFQLFVGLGLAILLYQLLTPIWWLCAVILLFIGFIFFLKQAQISQIEYLDQKLWSVAYFSKKEI
YRAEITKIIDYQLFVVIYLEETPTIIAIVWFDQLPIQQWKRLKVLEKLY

Download         Length: 390 bp

>T168902 NZ_CP076257:287431-287565 [Xanthomonas translucens pv. graminis]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTTTCGGTAGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9833.26 Da        Isoelectric Point: 4.7037

>AT168902 WP_014207740.1 NZ_CP059479:1170526-1170771 [Acinetobacter baumannii]
MTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLKQYVH
G

Download         Length: 246 bp

>AT168902 NZ_CP076257:287180-287332 [Xanthomonas translucens pv. graminis]
ATGAAGCGACTGTTCACCTTGATGATGCTGACCCTGTTCTGTGCAGGCATGCTGACTGGCTGCAACACCATGGCCGGTGC
TGGCAAGGATATGCAGAAGGCCGGCGATAAGGTGGAAAACAAGGCCGACGACTGCAAAGACGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB F0KQ03

References