168901

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 102240..102768 Replicon plasmid p17-84_OXA
Accession NZ_CP059478
Organism Acinetobacter baumannii strain 17-84

Toxin (Protein)


Gene name relE Uniprot ID N9N871
Locus tag H2Q98_RS00535 Protein ID WP_000221358.1
Coordinates 102240..102533 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID N9NWT9
Locus tag H2Q98_RS00540 Protein ID WP_000246755.1
Coordinates 102523..102768 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H2Q98_RS00505 98178..98405 - 228 WP_000248278.1 hypothetical protein -
H2Q98_RS00510 98429..98620 + 192 WP_000951934.1 hypothetical protein -
H2Q98_RS00515 99102..99644 - 543 WP_000587837.1 AAA family ATPase -
H2Q98_RS00520 99657..100517 - 861 WP_000557454.1 aminoglycoside N-acetyltransferase AAC(3)-IId -
H2Q98_RS00525 100623..101126 - 504 Protein_104 Tn3 family transposase -
H2Q98_RS00530 101324..102028 + 705 WP_001067858.1 IS6-like element IS26 family transposase -
H2Q98_RS00535 102240..102533 - 294 WP_000221358.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H2Q98_RS00540 102523..102768 - 246 WP_000246755.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
H2Q98_RS00545 102965..104314 - 1350 WP_001060713.1 chromate efflux transporter -
H2Q98_RS00550 104311..105237 - 927 WP_026055779.1 chromate resistance protein -
H2Q98_RS00555 105352..105918 - 567 WP_000678311.1 recombinase family protein -
H2Q98_RS00560 107383..107670 - 288 WP_000908082.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid blaOXA-58 / msr(E) / mph(E) / aph(6)-Id / aph(3'')-Ib / blaPER-1 / aph(3')-VIb / sul2 / aac(3)-IId - 1..108715 108715


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-72)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11292.52 Da        Isoelectric Point: 10.4753

>T168901 WP_000221358.1 NZ_CP059478:c102533-102240 [Acinetobacter baumannii]
MTYKLLRHKDFTAEWEKLPVAIRDQFKKKLAKVIEQPHIPKNMLRGDLAGCYKIKLLKAGVRLVYQVKDDQVVILLITVG
KRADSIVYDEAKKRIKD

Download         Length: 294 bp

>T168901 NZ_CP076257:287180-287332 [Xanthomonas translucens pv. graminis]
ATGAAGCGACTGTTCACCTTGATGATGCTGACCCTGTTCTGTGCAGGCATGCTGACTGGCTGCAACACCATGGCCGGTGC
TGGCAAGGATATGCAGAAGGCCGGCGATAAGGTGGAAAACAAGGCCGACGACTGCAAAGACGGCAAGTGCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9249.64 Da        Isoelectric Point: 4.3142

>AT168901 WP_000246755.1 NZ_CP059478:c102768-102523 [Acinetobacter baumannii]
MATVNFRIDEALKEKSYSILKEQGIAPTDFFTSILEYVATTGKLPVKKALLSEEDEELLALVRKRINDPKEMFEEVTLDD
L

Download         Length: 246 bp

>AT168901 NZ_CP076257:287431-287565 [Xanthomonas translucens pv. graminis]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTTTCGGTAGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6A1RKP4

Antitoxin

Source ID Structure
AlphaFold DB A0A6A1RJ80

References