Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 2126946..2127599 Replicon chromosome
Accession NZ_CP059474
Organism Acinetobacter baumannii strain M175-3

Toxin (Protein)


Gene name cptA Uniprot ID D0CD27
Locus tag H1D55_RS09860 Protein ID WP_000607073.1
Coordinates 2126946..2127335 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag H1D55_RS09865 Protein ID WP_001288210.1
Coordinates 2127342..2127599 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H1D55_RS09845 2122063..2124258 - 2196 WP_001158905.1 TRAP transporter large permease subunit -
H1D55_RS09850 2124446..2125012 - 567 WP_000651536.1 rhombosortase -
H1D55_RS09855 2125091..2126176 - 1086 WP_000049106.1 hypothetical protein -
H1D55_RS09860 2126946..2127335 - 390 WP_000607073.1 membrane protein Toxin
H1D55_RS09865 2127342..2127599 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
H1D55_RS09870 2127787..2128959 + 1173 WP_001190553.1 acyl-CoA dehydrogenase family protein -
H1D55_RS09875 2129009..2130499 - 1491 WP_000415127.1 NAD(P)/FAD-dependent oxidoreductase -
H1D55_RS09880 2130681..2131058 - 378 WP_001216380.1 50S ribosomal protein L17 -
H1D55_RS09885 2131077..2132084 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15635.91 Da        Isoelectric Point: 10.3890

>T168894 WP_000607073.1 NZ_CP059474:c2127335-2126946 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T168894 NZ_CP076254:c221398-221246 [Xanthomonas translucens pv. graminis]
ATGAAGCGACTGTTCACCTTGATGATGCTGACCCTGTTCTGTGCAGGCATGCTGACTGGCTGCAACACCATGGCCGGTGC
TGGCAAGGATATGCAGAAGGCCGGCGATAAGGTGGAAAACAAGGCCGACGACTGCAAAGACGGCAAGTGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT168894 WP_001288210.1 NZ_CP059474:c2127599-2127342 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp

>AT168894 NZ_CP076254:c221147-221013 [Xanthomonas translucens pv. graminis]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTTTCGGTAGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB D0CD27

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References