Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4068843..4068988 Replicon chromosome
Accession NZ_CP059468
Organism Klebsiella pneumoniae strain BA25665

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4068850..4068952 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4068843..4068988 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HBJ46_RS19620 4064374..4065807 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HBJ46_RS19625 4065923..4066162 + 240 WP_002911393.1 YebV family protein -
HBJ46_RS19630 4066260..4066451 + 192 WP_002911395.1 YebW family protein -
HBJ46_RS19635 4066448..4067101 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
HBJ46_RS19640 4067258..4068226 + 969 WP_004151446.1 VirK/YbjX family protein -
HBJ46_RS19645 4068331..4068474 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4068843..4068988 + 146 - - Antitoxin
- 4068850..4068952 - 103 - - Toxin
HBJ46_RS19650 4069111..4069449 - 339 WP_002911404.1 YebY family protein -
HBJ46_RS19655 4069466..4070335 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
HBJ46_RS19660 4070339..4070713 - 375 WP_004151448.1 CopC domain-containing protein YobA -
HBJ46_RS19665 4070826..4071056 + 231 WP_002911406.1 DNA polymerase III subunit theta -
HBJ46_RS19670 4071135..4071794 + 660 WP_043906809.1 exodeoxyribonuclease X -
HBJ46_RS19675 4071798..4073858 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4061617..4142043 80426


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T168881 NZ_CP059468:c4068952-4068850 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT168881 NZ_CP059468:4068843-4068988 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References