Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 3796300..3797408 | Replicon | chromosome |
| Accession | NZ_CP059467 | ||
| Organism | Aromatoleum bremense strain PbN1 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | pbN1_RS17940 | Protein ID | WP_210147571.1 |
| Coordinates | 3796656..3797408 (+) | Length | 251 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | pbN1_RS17935 | Protein ID | WP_041646544.1 |
| Coordinates | 3796300..3796659 (+) | Length | 120 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| pbN1_RS17900 (pbN1_36390) | 3791310..3791531 | - | 222 | WP_169120328.1 | hypothetical protein | - |
| pbN1_RS17905 (pbN1_36400) | 3791558..3791956 | - | 399 | WP_169202899.1 | thioredoxin family protein | - |
| pbN1_RS17910 (pbN1_36410) | 3792148..3792915 | + | 768 | WP_169202898.1 | metallophosphoesterase family protein | - |
| pbN1_RS17915 (pbN1_36420) | 3792961..3793575 | - | 615 | WP_169202897.1 | hypothetical protein | - |
| pbN1_RS17920 (pbN1_36430) | 3793668..3794000 | - | 333 | WP_169202896.1 | cupin domain-containing protein | - |
| pbN1_RS17925 (pbN1_36440) | 3794009..3794761 | - | 753 | WP_169202895.1 | SDR family oxidoreductase | - |
| pbN1_RS17930 (pbN1_36460) | 3795058..3796215 | + | 1158 | WP_169202894.1 | PQQ-dependent sugar dehydrogenase | - |
| pbN1_RS17935 (pbN1_36470) | 3796300..3796659 | + | 360 | WP_041646544.1 | MbcA/ParS/Xre antitoxin family protein | Antitoxin |
| pbN1_RS17940 (pbN1_36480) | 3796656..3797408 | + | 753 | WP_210147571.1 | RES family NAD+ phosphorylase | Toxin |
| pbN1_RS17945 (pbN1_36490) | 3797510..3797776 | - | 267 | WP_169119260.1 | Txe/YoeB family addiction module toxin | - |
| pbN1_RS17950 (pbN1_36500) | 3797770..3798012 | - | 243 | WP_169202893.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| pbN1_RS17955 (pbN1_36510) | 3798163..3798459 | - | 297 | WP_169202892.1 | hypothetical protein | - |
| pbN1_RS17960 | 3798515..3798880 | - | 366 | WP_169202891.1 | hypothetical protein | - |
| pbN1_RS17965 (pbN1_36520) | 3798957..3799358 | - | 402 | WP_169202890.1 | hypothetical protein | - |
| pbN1_RS17970 (pbN1_36530) | 3799355..3799684 | - | 330 | WP_169202889.1 | hypothetical protein | - |
| pbN1_RS21010 | 3799788..3799919 | - | 132 | WP_280516165.1 | hypothetical protein | - |
| pbN1_RS17975 (pbN1_36540) | 3800146..3801091 | - | 946 | Protein_3533 | IS5 family transposase | - |
| pbN1_RS17980 | 3801151..3801669 | - | 519 | WP_210147572.1 | SHOCT domain-containing protein | - |
| pbN1_RS17985 (pbN1_36550) | 3801681..3802091 | - | 411 | WP_169202887.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 3800075..3801091 | 1016 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 251 a.a. Molecular weight: 27583.49 Da Isoelectric Point: 5.8779
>T168871 WP_210147571.1 NZ_CP059467:3796656-3797408 [Aromatoleum bremense]
VTDIWAAVGGEAPVVELAGNLVRLVESQEQIATNRLVDTLEEQALLESLLESSKPPLPQAARGLHYLLATPFRYPPLRHG
SRFGGHFEPSLFYAAFDTATVLVESAYYRFVFWHGMAVAPASSLASQHTLFGAPWRCARGVQLQLPPFDHWREQLTDPAD
YAATQRLGTAMRKAGVEAFEYVSARDPAGGLNVALFTPMALAARRPDFMQAWLAETDAAEVRFYCQEERLVHRFPLGQFL
VAGGLPMPAV
VTDIWAAVGGEAPVVELAGNLVRLVESQEQIATNRLVDTLEEQALLESLLESSKPPLPQAARGLHYLLATPFRYPPLRHG
SRFGGHFEPSLFYAAFDTATVLVESAYYRFVFWHGMAVAPASSLASQHTLFGAPWRCARGVQLQLPPFDHWREQLTDPAD
YAATQRLGTAMRKAGVEAFEYVSARDPAGGLNVALFTPMALAARRPDFMQAWLAETDAAEVRFYCQEERLVHRFPLGQFL
VAGGLPMPAV
Download Length: 753 bp
>T168871 NZ_CP076249:c4419350-4419198 [Xanthomonas translucens pv. hordei]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTTTGTGCAGGCATGCTGACCGGCTGCAACACCATGGCCGGCGC
CGGTAAGGACATGCAGAAGGCCGGCGATAAGGTGGAAACCAAGGCCGACGACTGTAAAGACGGCAAGTGCTGA
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTTTGTGCAGGCATGCTGACCGGCTGCAACACCATGGCCGGCGC
CGGTAAGGACATGCAGAAGGCCGGCGATAAGGTGGAAACCAAGGCCGACGACTGTAAAGACGGCAAGTGCTGA
Antitoxin
Download Length: 120 a.a. Molecular weight: 12749.85 Da Isoelectric Point: 10.3723
>AT168871 WP_041646544.1 NZ_CP059467:3796300-3796659 [Aromatoleum bremense]
MSVAALRKPDATQVVTKALLNAGKEMGLTQAALGVVIGKDRTAISRNGIDPDSKAGELALLLIRAYRALFALVGGDAAQM
KHWMHTDNHHVGGVPAEQIRTVQGLLRVVEYLDAIRGRL
MSVAALRKPDATQVVTKALLNAGKEMGLTQAALGVVIGKDRTAISRNGIDPDSKAGELALLLIRAYRALFALVGGDAAQM
KHWMHTDNHHVGGVPAEQIRTVQGLLRVVEYLDAIRGRL
Download Length: 360 bp
>AT168871 NZ_CP076249:c4419099-4418965 [Xanthomonas translucens pv. hordei]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|