Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3700057..3700730 Replicon chromosome
Accession NZ_CP059467
Organism Aromatoleum bremense strain PbN1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag pbN1_RS17350 Protein ID WP_169203224.1
Coordinates 3700302..3700730 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag pbN1_RS17345 Protein ID WP_169203225.1
Coordinates 3700057..3700302 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
pbN1_RS17320 (pbN1_35160) 3695126..3696391 - 1266 WP_169203230.1 hypothetical protein -
pbN1_RS17325 (pbN1_35170) 3696684..3697688 - 1005 WP_169203229.1 Rpn family recombination-promoting nuclease/putative transposase -
pbN1_RS17330 (pbN1_35190) 3698161..3699267 + 1107 WP_169203228.1 glycosyltransferase -
pbN1_RS17335 (pbN1_35200) 3699480..3699737 + 258 WP_169203227.1 DUF4160 domain-containing protein -
pbN1_RS17340 (pbN1_35210) 3699742..3699999 + 258 WP_169203226.1 DUF2442 domain-containing protein -
pbN1_RS17345 (pbN1_35220) 3700057..3700302 + 246 WP_169203225.1 DUF6364 family protein Antitoxin
pbN1_RS17350 (pbN1_35230) 3700302..3700730 + 429 WP_169203224.1 PIN domain-containing protein Toxin
pbN1_RS17355 (pbN1_35250) 3701025..3702470 + 1446 WP_169203223.1 MBL fold metallo-hydrolase -
pbN1_RS17360 (pbN1_35260) 3702753..3704135 + 1383 WP_210147558.1 Fic family protein -
pbN1_RS17365 (pbN1_35270) 3704143..3705420 + 1278 WP_169203221.1 Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-126)

Antitoxin

Protein of unknown function DUF6364

(4-44)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15576.88 Da        Isoelectric Point: 7.4835

>T168868 WP_169203224.1 NZ_CP059467:3700302-3700730 [Aromatoleum bremense]
MRALLDVNVLIALLDGSHVHHARASRWLAGEIEHGWASCPLTQNGCLRIMAQPAYPQALPLGAVASRLAQATAHPAHQFI
ADDYSLLDGAQITWQNLLGHRQITDTYLLGLAVRHDCRFVSFDARINPGIVTGAQPKHWCTL

Download         Length: 429 bp

>T168868 NZ_CP076249:2268532-2268951 [Xanthomonas translucens pv. hordei]
ATGATTGTCTTGGATACGAATGTCGTCTCCGAGGCGATGAAACCCGAACCCGACCCGGCCGTGCGAGCTTGGTTGAATGA
GCAGGTAGCGGAAACCCTCTACCTGTCCAGCGTGACGCTTGCCGAACTGCTGTTCGGCATCGGCGCGCTGCCGAACGGGA
AACGTAAAAAAGGCCTGGGCGAAGCCCTGGACGGATTGCTCGAACTGTTCAGCGAGCGGGTGCTGATGTTCGACACCGAA
GCAGCTCGCAATTATGCCGAGCTGGCGGTGAAGGCCCGCATAGCCGGGAAGGGTTTTCCAACACCCGACGGATATATTGG
GGCTATTGCGGCCTCCAAGGGATTTATCGTAGCAACACGCGACACCAGCCCTTTTGAAGCGGCCGGGCTTACTGTTATCA
ATCCTTGGAACCATCGGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8745.96 Da        Isoelectric Point: 6.4594

>AT168868 WP_169203225.1 NZ_CP059467:3700057-3700302 [Aromatoleum bremense]
MRTTIDIESDVLAAAKEIARQQHTSVGKVISRLVRQSLTGAAAPQTVAHQTPAVPGFEPFPARDVIVTNELIDRLRDAEG
I

Download         Length: 246 bp

>AT168868 NZ_CP076249:2268281-2268535 [Xanthomonas translucens pv. hordei]
ATGGCAATCCTGACAGTGCGGAATGTGCCCGACGAGGTACATCGCGCTCTGCGCTTACGGGCCGCCGAGCATGGCCGCAG
TACAGAGGCGGAGGTCCGCGAGATTCTGGAGAGTGCAGTTAAGTCACAAAAGCGCATCCGCATGGGCGACGCGTTGGCGG
AGCTTGGCCGCCGCGTAGGGCTAACAAACGATGATTTCGCAGTATTGGACCAGGTGCGCGACAAGGTGCCGGCAGAACCG
ATGAGGTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References