Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PrlF(antitoxin)
Location 3585371..3585938 Replicon chromosome
Accession NZ_CP059467
Organism Aromatoleum bremense strain PbN1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag pbN1_RS16845 Protein ID WP_169202789.1
Coordinates 3585591..3585938 (+) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag pbN1_RS16840 Protein ID WP_169202790.1
Coordinates 3585371..3585601 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
pbN1_RS16820 3581380..3581643 - 264 WP_169202820.1 hypothetical protein -
pbN1_RS16825 (pbN1_34170) 3581906..3583189 + 1284 WP_169202791.1 serine--tRNA ligase -
pbN1_RS16830 (pbN1_34180) 3583275..3584705 - 1431 WP_169202819.1 membrane-bound lytic murein transglycosylase MltF -
pbN1_RS16840 (pbN1_34190) 3585371..3585601 + 231 WP_169202790.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
pbN1_RS16845 (pbN1_34200) 3585591..3585938 + 348 WP_169202789.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
pbN1_RS16850 (pbN1_34210) 3586031..3586576 - 546 WP_169202788.1 hypothetical protein -
pbN1_RS16855 (pbN1_34220) 3587028..3588035 + 1008 WP_169202787.1 L-histidine N(alpha)-methyltransferase -
pbN1_RS16860 (pbN1_34240) 3588251..3590161 + 1911 WP_169202786.1 1,4-alpha-glucan branching protein GlgB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-109)

Antitoxin

PrlF antitoxin

(5-47)


Sequences

Toxin        


Download         Length: 116 a.a.        Molecular weight: 12354.25 Da        Isoelectric Point: 10.3000

>T168867 WP_169202789.1 NZ_CP059467:3585591-3585938 [Aromatoleum bremense]
VSFERFAVVRVPFPFTDRNATKNRPALVLSNAAAFNTPAGHSVMAMITSEANAPWPLDCRIADLAAAGLPAPSKVRFKLF
TLDHRLVRGQIGKLSPSDSEVVRAGLTALLDEAQP

Download         Length: 348 bp

>T168867 NZ_CP076249:1071334-1071483 [Xanthomonas translucens pv. hordei]
TTGGACGACGAGACCTACGCCAAGTTACAGGTGTTGCTGCAGGAAAATCTAGAAGTCGGAGATCTGATCGAAGGAACCGG
TGGCCTGCGCAAGGTGCGCGTCGCCGCGAAAGGGCATGGCAAGCGAGGTGGCGCCCGTGTCATCTATTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8234.29 Da        Isoelectric Point: 4.3855

>AT168867 WP_169202790.1 NZ_CP059467:3585371-3585601 [Aromatoleum bremense]
MLAVAKITAKGQTTIPQDVRAALHVKPGDLIAWDVGADGTATVRRVQPLDVEYLRAVEGTLSEWAGEADEEAYREL

Download         Length: 231 bp

>AT168867 NZ_CP076249:1071603-1071785 [Xanthomonas translucens pv. hordei]
ATGAGCAAGTTCTTCGAAGCGCTGATGGAAAGCGTGCAGCAGATGGACGAGATCGTCCGTGGCGAGCGTGCTCCTTCGCG
CGAGTTCCATGTCGATGCGATCCAGGTCAAGCAAGTGCGTCTACCGGCCTCTCCCAGTCTAAGAGCGGCTAACAAAACTA
TGGAAGTCGCCGCAGGCAGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References