Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3236659..3237326 Replicon chromosome
Accession NZ_CP059467
Organism Aromatoleum bremense strain PbN1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag pbN1_RS15170 Protein ID WP_211161522.1
Coordinates 3236659..3237090 (-) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag pbN1_RS15175 Protein ID WP_169203819.1
Coordinates 3237096..3237326 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
pbN1_RS15150 (pbN1_30800) 3231779..3232546 + 768 WP_169203827.1 RNA polymerase sigma factor FliA -
pbN1_RS15155 (pbN1_30810) 3232571..3233311 + 741 WP_169119501.1 flagellar motor protein -
pbN1_RS15160 (pbN1_30820) 3233371..3234216 + 846 WP_169203822.1 flagellar motor protein MotD -
pbN1_RS15165 (pbN1_30830) 3234302..3236662 - 2361 WP_169203821.1 DNA topoisomerase IV subunit A -
pbN1_RS15170 (pbN1_30840) 3236659..3237090 - 432 WP_211161522.1 type II toxin-antitoxin system VapC family toxin Toxin
pbN1_RS15175 (pbN1_30850) 3237096..3237326 - 231 WP_169203819.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
pbN1_RS15180 (pbN1_30860) 3237448..3238263 - 816 WP_169203818.1 TIGR01458 family HAD-type hydrolase -
pbN1_RS15185 (pbN1_30870) 3238399..3240375 - 1977 WP_169203817.1 DNA topoisomerase IV subunit B -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-121)

Antitoxin

SpoVT-AbrB domain

(7-42)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15967.30 Da        Isoelectric Point: 6.4788

>T168866 WP_211161522.1 NZ_CP059467:c3237090-3236659 [Aromatoleum bremense]
MLDTNLCIYLINHRPAHVRARFDAHPIGDIGVSVITAAELAYGVTKSASARNRAALETFLLPLEVAPFDDKAIWRYAELR
TQLMRRGTPIGALDTQIAAHALALDCTLVTNNMREFERVDGLRLENWADQRLMESPASYFTAP

Download         Length: 432 bp

>T168866 NZ_CP076249:c1069236-1068985 [Xanthomonas translucens pv. hordei]
ATGGACACCATCACCTATAGCGCTGCACGCGCCGCCCTTGCGGACACCATGGAGCGTGTCGTCAACAATCACGAGCCGGT
GATCATCACCCGCAGCCGCGAGCAATCCGTGGTCATGCTGTCGCTGGAGGACTACAAGGCGATGGAGGAAACCGCCTACC
TGCTGCGCAGCCCGAAGAGCGCGCAGCGCCTGCTGGAATCCATCGCCCAGCTAGAGGCCGGTCGCGGCAAGGCACGGGAC
CTGGCCGAGTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8545.73 Da        Isoelectric Point: 4.7954

>AT168866 WP_169203819.1 NZ_CP059467:c3237326-3237096 [Aromatoleum bremense]
MDTAKLFTNGRSQAVRLPKEFRFEGDEVFIKRVGDAVVLLPRHGWGTLFGALEAFEPGFTIERDAPEQAEREALLP

Download         Length: 231 bp

>AT168866 NZ_CP076249:c1068988-1068731 [Xanthomonas translucens pv. hordei]
GTGACGCTTCAGTTCTCGGACAATGCCTGGGAGGACGACCTCTACTGGCAGCAGACCGACAAGAAGATGCTCAAGCGCAT
CAACGACCTGATCAAAGCCATTCAACGCGATCCCTTCCAGGGCGTCGGCAAGCCAGAACGGCTACGCCATGCCTTGGCCG
GCTATTGGTCGCGGCGCATCAACGACGAACACCGCATCGTCTACAAGGTCGAGGCCGGCATGCTGCTGATCGCGCAGGTG
CGCTACCACTACGTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References