Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) FicTA/Fic(toxin)
Location 23166..24054 Replicon plasmid pCFF_09A980_P1
Accession NZ_CP059446
Organism Campylobacter fetus strain CFF09A980

Toxin (Protein)


Gene name Fic Uniprot ID -
Locus tag GZ984_RS09300 Protein ID WP_181913251.1
Coordinates 23398..24054 (+) Length 219 a.a.

Antitoxin (Protein)


Gene name Fti Uniprot ID -
Locus tag GZ984_RS09295 Protein ID WP_181912979.1
Coordinates 23166..23414 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZ984_RS09280 18305..20494 + 2190 WP_181912981.1 DUF1738 domain-containing protein -
GZ984_RS09285 20504..22330 + 1827 WP_065839001.1 type IV secretory system conjugative DNA transfer family protein -
GZ984_RS09290 22342..23049 + 708 WP_181913250.1 conjugal transfer protein TraL -
GZ984_RS09295 23166..23414 + 249 WP_181912979.1 hypothetical protein Antitoxin
GZ984_RS09300 23398..24054 + 657 WP_181913251.1 Fic family protein Toxin
GZ984_RS09305 24115..24573 + 459 WP_059435589.1 S26 family signal peptidase -
GZ984_RS09310 24570..24941 + 372 WP_002850989.1 hypothetical protein -
GZ984_RS09315 25052..25738 + 687 WP_181913252.1 AAA family ATPase -
GZ984_RS09320 25741..25950 + 210 WP_181913253.1 hypothetical protein -
GZ984_RS09325 26030..27592 - 1563 WP_181913254.1 relaxase/mobilization nuclease domain-containing protein -
GZ984_RS09330 27567..27935 - 369 WP_181913238.1 DNA transfer protein -
GZ984_RS09335 28150..28365 + 216 WP_046037533.1 hypothetical protein -
GZ984_RS09340 28358..28633 + 276 WP_046037534.1 type II toxin-antitoxin system YafQ family toxin -
GZ984_RS09345 28630..28980 + 351 WP_181913239.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..52345 52345


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(50-158)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 25181.09 Da        Isoelectric Point: 10.1737

>T168853 WP_181913251.1 NZ_CP059446:23398-24054 [Campylobacter fetus]
MKESNEELFKKLIADNKLGIKDEKLFDKESRKYTLVRTKEIIKTPIKGNFDYQHLKNIHKYIFQDVFHWAGKDRMEVGLH
GNFGKYAPNGTITNFVPGKDLNATAQQIFTWLKEDNYLKNSKDLNDFAKNLAEFARNLNALHPFREGNGRTQRIFLNELT
KNVGYKLDLNLIPKNKMIMASVEASQLKLGKLEALIKTNLKSFKQNLEKENTLGLSLC

Download         Length: 657 bp

>T168853 NZ_CP076245:c4860935-4860585 [Escherichia coli O157:H7]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GTGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTT
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9614.88 Da        Isoelectric Point: 4.3896

>AT168853 WP_181912979.1 NZ_CP059446:23166-23414 [Campylobacter fetus]
MTYPEVHSLEESLAILKKYKDDVSKKDYEEIKSTICGHAIEDIFANEEDIIMLVKMSTYNLSSDEILAEYKEKGFVEYER
KQ

Download         Length: 249 bp

>AT168853 NZ_CP076245:c4861180-4860929 [Escherichia coli O157:H7]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGTGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References