Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) FicTA/Fic(toxin)
Location 18236..19124 Replicon plasmid pCFF_00A031_P1
Accession NZ_CP059444
Organism Campylobacter fetus strain CFF00A031

Toxin (Protein)


Gene name Fic Uniprot ID -
Locus tag GZ985_RS09050 Protein ID WP_181913251.1
Coordinates 18468..19124 (+) Length 219 a.a.

Antitoxin (Protein)


Gene name Fti Uniprot ID -
Locus tag GZ985_RS09045 Protein ID WP_181912979.1
Coordinates 18236..18484 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GZ985_RS09030 13375..15564 + 2190 WP_181913400.1 DUF1738 domain-containing protein -
GZ985_RS09035 15574..17400 + 1827 WP_065839001.1 type IV secretory system conjugative DNA transfer family protein -
GZ985_RS09040 17412..18119 + 708 WP_181913250.1 conjugal transfer protein TraL -
GZ985_RS09045 18236..18484 + 249 WP_181912979.1 hypothetical protein Antitoxin
GZ985_RS09050 18468..19124 + 657 WP_181913251.1 Fic family protein Toxin
GZ985_RS09055 19185..19643 + 459 WP_059435589.1 S26 family signal peptidase -
GZ985_RS09060 19640..20011 + 372 WP_002850989.1 hypothetical protein -
GZ985_RS09065 20122..20808 + 687 WP_181913252.1 AAA family ATPase -
GZ985_RS09070 20811..21020 + 210 WP_181913390.1 hypothetical protein -
GZ985_RS09075 21100..22662 - 1563 WP_181913391.1 relaxase/mobilization nuclease domain-containing protein -
GZ985_RS09080 22637..23005 - 369 WP_181913238.1 DNA transfer protein -
GZ985_RS09085 23231..23446 + 216 WP_181913392.1 hypothetical protein -
GZ985_RS09090 23439..23714 + 276 WP_181913393.1 type II toxin-antitoxin system YafQ family toxin -
GZ985_RS09095 23711..24040 + 330 WP_181913394.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..26793 26793


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(50-158)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 25181.09 Da        Isoelectric Point: 10.1737

>T168851 WP_181913251.1 NZ_CP059444:18468-19124 [Campylobacter fetus]
MKESNEELFKKLIADNKLGIKDEKLFDKESRKYTLVRTKEIIKTPIKGNFDYQHLKNIHKYIFQDVFHWAGKDRMEVGLH
GNFGKYAPNGTITNFVPGKDLNATAQQIFTWLKEDNYLKNSKDLNDFAKNLAEFARNLNALHPFREGNGRTQRIFLNELT
KNVGYKLDLNLIPKNKMIMASVEASQLKLGKLEALIKTNLKSFKQNLEKENTLGLSLC

Download         Length: 657 bp

>T168851 NZ_CP076245:c4611667-4611353 [Escherichia coli O157:H7]
ATGCAATTTACGGTATACCGCAGTCGCAGCAGGAACGCCGCGTTTCCCTTTGTTATCGATGTTACCAGCGACATTATTGG
TGTGATTAATCGCCGTATTGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGGTAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAAGGAGCATTAGATTTTATGCTCGACGGGATTTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9614.88 Da        Isoelectric Point: 4.3896

>AT168851 WP_181912979.1 NZ_CP059444:18236-18484 [Campylobacter fetus]
MTYPEVHSLEESLAILKKYKDDVSKKDYEEIKSTICGHAIEDIFANEEDIIMLVKMSTYNLSSDEILAEYKEKGFVEYER
KQ

Download         Length: 249 bp

>AT168851 NZ_CP076245:c4611903-4611670 [Escherichia coli O157:H7]
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACG
CTGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References