Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3219667..3220580 Replicon chromosome
Accession NZ_CP059414
Organism Enterobacter hormaechei strain ENCL48212

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag H1D56_RS17340 Protein ID WP_045142243.1
Coordinates 3220107..3220580 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag H1D56_RS17335 Protein ID WP_023296216.1
Coordinates 3219667..3220110 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H1D56_RS17320 3215474..3217195 + 1722 WP_003858307.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -
H1D56_RS17325 3217241..3217945 + 705 WP_040117448.1 leucyl/phenylalanyl-tRNA--protein transferase -
H1D56_RS17330 3218230..3218448 + 219 WP_002211347.1 translation initiation factor IF-1 -
H1D56_RS17335 3219667..3220110 + 444 WP_023296216.1 DUF2384 domain-containing protein Antitoxin
H1D56_RS17340 3220107..3220580 + 474 WP_045142243.1 RES domain-containing protein Toxin
H1D56_RS17345 3220603..3221157 - 555 WP_045142244.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
H1D56_RS17350 3221167..3222165 - 999 WP_045142245.1 type I-F CRISPR-associated protein Csy3 -
H1D56_RS17355 3222179..3223114 - 936 WP_045142246.1 type I-F CRISPR-associated protein Csy2 -
H1D56_RS17360 3223111..3224421 - 1311 WP_045142247.1 type I-F CRISPR-associated protein Csy1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-145)

Antitoxin

Antitoxin Xre

(15-147)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17569.93 Da        Isoelectric Point: 5.1018

>T168802 WP_045142243.1 NZ_CP059414:3220107-3220580 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSIDIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFHKALNSVELMPFNFDTRLAEKTAP

Download         Length: 474 bp

>T168802 NZ_CP076241:4163182-4163400 [Escherichia coli O157:H7]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16512.81 Da        Isoelectric Point: 6.4819

>AT168802 WP_023296216.1 NZ_CP059414:3219667-3220110 [Enterobacter hormaechei]
MRTWVPAQRPADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Download         Length: 444 bp

>AT168802 NZ_CP076241:4162782-4163156 [Escherichia coli O157:H7]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACTCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References