Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 5268480..5269186 Replicon chromosome
Accession NZ_CP059398
Organism Bradyrhizobium sp. I71

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FJV43_RS25380 Protein ID WP_239621805.1
Coordinates 5268480..5268905 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FJV43_RS25385 Protein ID WP_239621806.1
Coordinates 5268902..5269186 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJV43_RS25355 (FJV43_25230) 5265175..5265585 + 411 WP_239621802.1 acyl-CoA thioesterase -
FJV43_RS25360 (FJV43_25235) 5265809..5266000 + 192 WP_024341426.1 hypothetical protein -
FJV43_RS25365 (FJV43_25240) 5266230..5266682 - 453 WP_239621803.1 nuclear transport factor 2 family protein -
FJV43_RS25370 (FJV43_25245) 5266837..5267523 + 687 WP_239621804.1 HAD-IA family hydrolase -
FJV43_RS25375 (FJV43_25250) 5267631..5268476 + 846 WP_126260507.1 DeoR/GlpR family DNA-binding transcription regulator -
FJV43_RS25380 (FJV43_25255) 5268480..5268905 - 426 WP_239621805.1 type II toxin-antitoxin system VapC family toxin Toxin
FJV43_RS25385 (FJV43_25260) 5268902..5269186 - 285 WP_239621806.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FJV43_RS25390 (FJV43_25265) 5269419..5270969 + 1551 WP_239621807.1 glycerol-3-phosphate dehydrogenase -
FJV43_RS25395 (FJV43_25270) 5270966..5272042 + 1077 WP_239621808.1 ABC transporter ATP-binding protein -
FJV43_RS25400 (FJV43_25275) 5272055..5273140 + 1086 WP_239621809.1 ABC transporter ATP-binding protein -
FJV43_RS25405 (FJV43_25280) 5273140..5274114 + 975 WP_239621810.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(15-78)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15452.79 Da        Isoelectric Point: 7.3221

>T168777 WP_239621805.1 NZ_CP059398:c5268905-5268480 [Bradyrhizobium sp. I71]
VNLLLDTNVLSEVRRPAPSPKVLAWLDTIDEDRAFISVASIAELRRGIALLDDARRRTALAAWLVHDLPARFAGRILPID
HAVAERWGDLMAQSRRTGVALSVMDGFFAASALVSNLTLVTRNVKDFTAFGVPLHNPWGDA

Download         Length: 426 bp

>T168777 NZ_CP076237:4182620-4182838 [Escherichia coli O157:H7]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10429.84 Da        Isoelectric Point: 5.8633

>AT168777 WP_239621806.1 NZ_CP059398:c5269186-5268902 [Bradyrhizobium sp. I71]
MVDRNTAPDPLPADDIWTLANAKARLSEVVDRAQAGPQIITRHGKPNAVVVSAEEWARKTARKGTLADFLLASPLRGTDL
ELERMRDEPRNEMP

Download         Length: 285 bp

>AT168777 NZ_CP076237:4182220-4182594 [Escherichia coli O157:H7]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACTCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References