Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 3661123..3661781 Replicon chromosome
Accession NZ_CP059398
Organism Bradyrhizobium sp. I71

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag FJV43_RS17770 Protein ID WP_239628927.1
Coordinates 3661123..3661527 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag FJV43_RS17775 Protein ID WP_239628929.1
Coordinates 3661527..3661781 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJV43_RS17750 (FJV43_17695) 3656411..3658981 - 2571 WP_239628915.1 FtsX-like permease family protein -
FJV43_RS17755 (FJV43_17700) 3658978..3659700 - 723 WP_239628917.1 ABC transporter ATP-binding protein -
FJV43_RS17760 (FJV43_17705) 3659756..3660391 + 636 WP_239629461.1 arylesterase -
FJV43_RS17765 (FJV43_17710) 3660564..3661100 + 537 WP_239628919.1 RNA 2',3'-cyclic phosphodiesterase -
FJV43_RS17770 (FJV43_17715) 3661123..3661527 - 405 WP_239628927.1 type II toxin-antitoxin system VapC family toxin Toxin
FJV43_RS17775 (FJV43_17720) 3661527..3661781 - 255 WP_239628929.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
FJV43_RS17780 (FJV43_17725) 3661959..3663146 + 1188 WP_239628931.1 cell division protein ZapE -
FJV43_RS17785 (FJV43_17730) 3663399..3664367 + 969 WP_028177733.1 malate dehydrogenase -
FJV43_RS17790 (FJV43_17735) 3664570..3665766 + 1197 WP_239628932.1 ADP-forming succinate--CoA ligase subunit beta -
FJV43_RS17795 (FJV43_17740) 3665771..3666250 + 480 WP_239628933.1 DUF1579 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14546.64 Da        Isoelectric Point: 4.7492

>T168776 WP_239628927.1 NZ_CP059398:c3661527-3661123 [Bradyrhizobium sp. I71]
MVIDTSAIVAIAFNEADAASMERLIADDPIRLISAATVLEATMVIETRLGDAGGRELDLWLVKVGAEIVAVDAFQADAAR
RAWRRYGKGRHTASLDYGDCFSYALAMTRSEPLLFKGEDFAKTDVSRPVAAPLR

Download         Length: 405 bp

>T168776 NZ_CP076237:3727517-3727903 [Escherichia coli O157:H7]
ATGGGTGTGTATAAGGCAAGGCGATTCAGCCAAAGCACGAAAAAACTTGGTATTCACGATAAAGTTCTCATGGCTGCCGC
TGAAGAAGTGATGCAAGGCATATGGGAGGCTGATTTAGGTAGCGGTGTCATCAAAAAACGGTTACCCCTCCAACAAGGAA
AGAGTGGTGGAGCCAGAACAATTATCTTTTTTAAATCAGCAAATCATGTGTTTTTTTATGATGGTTGGTCCAAGAGTGGT
CTAAGCAGTAAAGGAAGCAAAGAAATCGAAGATGATGAACTGGCAGCCTACAAAAAAATGGCAAATGCATTTCTGGCCTT
TAGCAATAAGCAAATAGAGGATTTGATCGAAACTGGCTTCTTGATTGAGGTGAAAAATGAGCGATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9707.98 Da        Isoelectric Point: 5.2273

>AT168776 WP_239628929.1 NZ_CP059398:c3661781-3661527 [Bradyrhizobium sp. I71]
MALSIKDPETEQLARSLAQLTGETITTATKRAIEERLRRLGSQTRKDALLEDMAEIRRRWSEMRVVDDRSPEEILGYDEH
GLPR

Download         Length: 255 bp

>AT168776 NZ_CP076237:3727893-3728222 [Escherichia coli O157:H7]
ATGAGCGATAAATTACAAATGATGCTGGAAGATGCAAAGGAACTGAATGCACTGGGCCTGATGTCTGATAGTGAGGTTGA
TGCCATTGCCGTCATGGTCAAAGCCCGTGAAGTCAGCGCCCGTATAGCCAAAGTCAAATCAATGACGGGTGAAGAGATCA
AAGCCATCCGCACCCGATACGGCATGTCACAATCCGTGCTGGCACATACAATGGGAATGTCAAAAGAAAGTGTCTCGAAA
TGGGAACGTAATGAAATAAAACCGAGCGGCCCGGCACTACGTATTTTGAATACATTGGCAATAAAAGGGCCGGAAGTTTT
TGCAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References