Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1963680..1963820 Replicon chromosome
Accession NZ_CP059391
Organism Klebsiella africana strain FF1003

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1963716..1963818 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1963680..1963820 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H1X61_RS09445 1958811..1960871 + 2061 WP_136030185.1 oligopeptidase B -
H1X61_RS09450 1960875..1961534 - 660 WP_136030187.1 exodeoxyribonuclease X -
H1X61_RS09455 1961613..1961843 - 231 WP_002911406.1 DNA polymerase III subunit theta -
H1X61_RS09460 1961957..1962331 + 375 WP_203033985.1 CopC domain-containing protein YobA -
H1X61_RS09465 1962333..1963202 + 870 WP_203033986.1 copper homeostasis membrane protein CopD -
H1X61_RS09470 1963219..1963557 + 339 WP_002911404.1 YebY family protein -
- 1963680..1963820 - 141 - - Antitoxin
- 1963716..1963818 + 103 - - Toxin
H1X61_RS09475 1964187..1965149 - 963 WP_025711084.1 glycosyltransferase -
H1X61_RS09480 1965424..1966557 - 1134 Protein_1850 IS3 family transposase -
H1X61_RS09485 1966777..1966920 - 144 WP_168435244.1 Ecr family regulatory small membrane protein -
H1X61_RS09490 1967025..1967993 - 969 WP_203033987.1 VirK/YbjX family protein -
H1X61_RS09495 1968150..1968803 + 654 WP_136030196.1 protein-serine/threonine phosphatase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1943083..1983810 40727


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T168762 NZ_CP059391:1963716-1963818 [Klebsiella africana]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 141 bp

>AT168762 NZ_CP059391:c1963820-1963680 [Klebsiella africana]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References