Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2847187..2847844 Replicon chromosome
Accession NZ_CP059348
Organism Providencia rettgeri strain ZG2016M39-3

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag H0913_RS13130 Protein ID WP_181477400.1
Coordinates 2847187..2847597 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag H0913_RS13135 Protein ID WP_181478795.1
Coordinates 2847578..2847844 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0913_RS13110 2843161..2844894 - 1734 WP_181477398.1 single-stranded-DNA-specific exonuclease RecJ -
H0913_RS13115 2844903..2845604 - 702 WP_154602567.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
H0913_RS13120 2845623..2846525 - 903 WP_181477399.1 site-specific tyrosine recombinase XerD -
H0913_RS13125 2846643..2847161 + 519 WP_154638134.1 flavodoxin FldB -
H0913_RS13130 2847187..2847597 - 411 WP_181477400.1 protein YgfX Toxin
H0913_RS13135 2847578..2847844 - 267 WP_181478795.1 FAD assembly factor SdhE Antitoxin
H0913_RS13140 2848136..2849122 + 987 WP_154638133.1 tRNA-modifying protein YgfZ -
H0913_RS13145 2849134..2849754 + 621 WP_154602562.1 HD domain-containing protein -
H0913_RS13150 2849825..2852701 - 2877 WP_181477401.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15485.46 Da        Isoelectric Point: 10.7520

>T168732 WP_181477400.1 NZ_CP059348:c2847597-2847187 [Providencia rettgeri]
VVLWKSNLSISWKTQLFSTCLHGVMGIILLVAPWAPGNSMIWLPLLVVLVASWAKSQKNISKVKGVAVLVNGNKLQWKKN
EWEIIKAPWCSRFGILLTLNALQGKPQKLRLWIAKDSVSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

>T168732 NZ_CP076234:55274-55579 [Escherichia coli O157:H7]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTACAGAGTGATATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGCTGTCAGATAAAGTCTCCCGTGAACTTTACCCGGTGG
TGCATATCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGCCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10780.29 Da        Isoelectric Point: 4.9149

>AT168732 WP_181478795.1 NZ_CP059348:c2847844-2847578 [Providencia rettgeri]
IDINNKARIHWACRRGMRELDISIMPFFEYEYDELTDHDKRVFVRLLEYPDPDLFNWLMNHGRPEDEELFSMIKLIQERN
KNRGPVEI

Download         Length: 267 bp

>AT168732 NZ_CP076234:55054-55272 [Escherichia coli O157:H7]
ATGAAGCAGCGTATTACAGTGACAGTTGACAGCGACAGCTATCAGTTGCTCAAGGCATATGATGTCAATATCTCCGGTCT
GGTAAGCACAACCATGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGAAAGCGGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCTGACGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References