Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2659109..2659766 Replicon chromosome
Accession NZ_CP059346
Organism Providencia alcalifaciens strain 1701003

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag H0910_RS12345 Protein ID WP_006661186.1
Coordinates 2659109..2659519 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag H0910_RS12350 Protein ID WP_036968342.1
Coordinates 2659500..2659766 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0910_RS12325 2655083..2656816 - 1734 WP_181480112.1 single-stranded-DNA-specific exonuclease RecJ -
H0910_RS12330 2656825..2657526 - 702 WP_006658051.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
H0910_RS12335 2657545..2658447 - 903 WP_006658050.1 site-specific tyrosine recombinase XerD -
H0910_RS12340 2658565..2659083 + 519 WP_006658049.1 flavodoxin FldB -
H0910_RS12345 2659109..2659519 - 411 WP_006661186.1 hypothetical protein Toxin
H0910_RS12350 2659500..2659766 - 267 WP_036968342.1 FAD assembly factor SdhE Antitoxin
H0910_RS12355 2660058..2661044 + 987 WP_181480113.1 tRNA-modifying protein YgfZ -
H0910_RS12360 2661056..2661676 + 621 WP_006658045.1 HD domain-containing protein -
H0910_RS12365 2661765..2664641 - 2877 WP_181480114.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15437.35 Da        Isoelectric Point: 10.6963

>T168718 WP_006661186.1 NZ_CP059346:c2659519-2659109 [Providencia alcalifaciens]
VVLWKSNLSISWKTQLFSTSLHVGAGIILLVAPWEPGNSMIWLPLLVILVASWAKSQKNISKVKGVAVLVNGNKLQWKKN
EWEIIKAPWCSRCGILLTLKALQGKPQKLRLWVAKDSVSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

>T168718 NZ_CP076232:2721037-2721411 [Escherichia coli O157:H7]
ATGAAAACATTATCCGACACACATGTACGGGAGGTATCTCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAT
CCGACTGCTGGACCAGCATTATGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTTAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACCTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10708.25 Da        Isoelectric Point: 5.1813

>AT168718 WP_036968342.1 NZ_CP059346:c2659766-2659500 [Providencia alcalifaciens]
IDINNKARIHWACRRGMRELDISIMPFFEHEYDELTDHDKRIFVRLLECPDPDLFNWLMNHGRPEDEELFSMIKLIQERN
KNRGPVEI

Download         Length: 267 bp

>AT168718 NZ_CP076232:2720616-2720990 [Escherichia coli O157:H7]
GTGTCAGACAAACTCTCCGGGATAACTCATCGTGATGACAATCACGACCGCCCCTGGTGGGGGCTTCCCTGCACAGTGAG
GCCCTGTTTTGGCGCTCGTCTGGTGCAAGAGGGTAACCGCCTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGCT
TCAGCGACGCAGATGCATACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGATATCAGCATACCGTCACGCTGAATGCAAAAGGGCTGACCTGCGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCAGCACCCGCAACCACCTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References