Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1950446..1950591 Replicon chromosome
Accession NZ_CP059317
Organism Klebsiella pneumoniae strain Kp46564

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1950482..1950584 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1950446..1950591 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H1D29_RS10945 1945576..1947636 + 2061 WP_004151449.1 oligopeptidase B -
H1D29_RS10950 1947640..1948299 - 660 WP_002911407.1 exodeoxyribonuclease X -
H1D29_RS10955 1948378..1948608 - 231 WP_002911406.1 DNA polymerase III subunit theta -
H1D29_RS10960 1948721..1949095 + 375 WP_060577972.1 CopC domain-containing protein YobA -
H1D29_RS10965 1949099..1949968 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
H1D29_RS10970 1949985..1950323 + 339 WP_002911404.1 YebY family protein -
- 1950446..1950591 - 146 - - Antitoxin
- 1950482..1950584 + 103 - - Toxin
H1D29_RS10975 1950960..1951103 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
H1D29_RS10980 1951208..1952176 - 969 WP_014907334.1 VirK/YbjX family protein -
H1D29_RS10985 1952333..1952986 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
H1D29_RS10990 1952983..1953174 - 192 WP_002911395.1 YebW family protein -
H1D29_RS10995 1953272..1953511 - 240 WP_002911393.1 YebV family protein -
H1D29_RS11000 1953627..1955060 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T168619 NZ_CP059317:1950482-1950584 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT168619 NZ_CP059317:c1950591-1950446 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References