Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1953955..1954100 Replicon chromosome
Accession NZ_CP059312
Organism Klebsiella pneumoniae strain Kp46596

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1953991..1954093 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1953955..1954100 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H1D28_RS12190 1949085..1951145 + 2061 WP_004151449.1 oligopeptidase B -
H1D28_RS12195 1951149..1951808 - 660 WP_002911407.1 exodeoxyribonuclease X -
H1D28_RS12200 1951887..1952117 - 231 WP_002911406.1 DNA polymerase III subunit theta -
H1D28_RS12205 1952230..1952604 + 375 WP_039819395.1 CopC domain-containing protein YobA -
H1D28_RS12210 1952608..1953477 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
H1D28_RS12215 1953494..1953832 + 339 WP_002911404.1 YebY family protein -
- 1953955..1954100 - 146 - - Antitoxin
- 1953991..1954093 + 103 - - Toxin
H1D28_RS12220 1954469..1954612 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
H1D28_RS12225 1954717..1955685 - 969 WP_014907334.1 VirK/YbjX family protein -
H1D28_RS12230 1955842..1956495 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
H1D28_RS12235 1956492..1956683 - 192 WP_002911395.1 YebW family protein -
H1D28_RS12240 1956781..1957020 - 240 WP_002911393.1 YebV family protein -
H1D28_RS12245 1957136..1958569 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T168599 NZ_CP059312:1953991-1954093 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT168599 NZ_CP059312:c1954100-1953955 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References