Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 894546..895084 Replicon chromosome
Accession NZ_CP059298
Organism Providencia rettgeri strain P01

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H0904_RS03980 Protein ID WP_140172124.1
Coordinates 894794..895084 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H0904_RS03975 Protein ID WP_181489335.1
Coordinates 894546..894797 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0904_RS03960 890960..891979 + 1020 WP_004905387.1 erythrose-4-phosphate dehydrogenase -
H0904_RS03965 892072..893235 + 1164 WP_004905385.1 phosphoglycerate kinase -
H0904_RS03970 893295..894371 + 1077 WP_094962157.1 class II fructose-bisphosphate aldolase -
H0904_RS03975 894546..894797 + 252 WP_181489335.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
H0904_RS03980 894794..895084 + 291 WP_140172124.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H0904_RS03985 895079..895435 - 357 WP_181489338.1 DUF4440 domain-containing protein -
H0904_RS03990 895432..896289 - 858 WP_036958581.1 LysR family transcriptional regulator -
H0904_RS03995 896374..897060 + 687 WP_004905375.1 ankyrin repeat domain-containing protein -
H0904_RS04000 897060..897527 + 468 WP_096864803.1 nucleoside deaminase -
H0904_RS04005 897524..898705 + 1182 WP_096864804.1 cyanate transporter -
H0904_RS04010 898802..899671 + 870 WP_181489340.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11124.23 Da        Isoelectric Point: 10.7261

>T168579 WP_140172124.1 NZ_CP059298:894794-895084 [Providencia rettgeri]
MTGFYKVKFRDDAAKEWKKLGATIQKQFAKKLKLLIENPHIPSARLSGLQNCYKIKLKASGYRLVYEVVDNQLIIIVVTV
GKRNRNEVYDIAKKRL

Download         Length: 291 bp

>T168579 NZ_CP076123:52168-52482 [Escherichia coli]
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATTGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGGTAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAAGGAGCATTAGATTTTATGCTCGACGGGATTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9312.67 Da        Isoelectric Point: 4.1683

>AT168579 WP_181489335.1 NZ_CP059298:894546-894797 [Providencia rettgeri]
MPQVILSDVTASISELKKNPMATVDSGEGFPVAILNRNKTAFYCVPAEIYENLLEQIEDKELIEIVNARKNQKLVDVDLD
SYL

Download         Length: 252 bp

>AT168579 NZ_CP076123:51932-52165 [Escherichia coli]
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACA
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References