Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 652713..654186 Replicon chromosome
Accession NZ_CP059298
Organism Providencia rettgeri strain P01

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag H0904_RS02885 Protein ID WP_181489245.1
Coordinates 653497..654186 (+) Length 230 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag H0904_RS02880 Protein ID WP_181489243.1
Coordinates 652713..653504 (+) Length 264 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0904_RS02845 647882..648205 - 324 WP_001896384.1 type II toxin-antitoxin system RelE/ParE family toxin -
H0904_RS02850 648386..648667 + 282 WP_000433891.1 type IV conjugative transfer system protein TraL -
H0904_RS02855 648664..649290 + 627 WP_159262613.1 pilus assembly protein -
H0904_RS02860 649274..650170 + 897 WP_159262630.1 type-F conjugative transfer system secretin TraK -
H0904_RS02865 650173..651462 + 1290 WP_159262611.1 TraB/VirB10 family protein -
H0904_RS02870 651537..652109 + 573 WP_148039504.1 type IV conjugative transfer system lipoprotein TraV -
H0904_RS02875 652106..652492 + 387 WP_032469918.1 hypothetical protein -
H0904_RS02880 652713..653504 + 792 WP_181489243.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
H0904_RS02885 653497..654186 + 690 WP_181489245.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
H0904_RS02890 654191..654433 + 243 WP_181489258.1 hypothetical protein -
H0904_RS02895 654565..655257 + 693 WP_001228924.1 DsbC family protein -
H0904_RS02900 655257..657656 + 2400 WP_000648043.1 type IV secretion system protein TraC -
H0904_RS02905 657649..657996 + 348 WP_001044649.1 hypothetical protein -
H0904_RS02910 657980..658492 + 513 WP_181159794.1 S26 family signal peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element blaCTX-M-3 / mph(E) / msr(E) - 565857..824232 258375


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-197)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(1-97)


Sequences

Toxin        


Download         Length: 230 a.a.        Molecular weight: 25800.59 Da        Isoelectric Point: 4.4749

>T168577 WP_181489245.1 NZ_CP059298:653497-654186 [Providencia rettgeri]
MDKDSPYYKQVSLLIRMLPVVATETVFALKGGTAINLFVRDFPRLYVDIDLAYLPLEPRDEALINVRAALQRITDRINTQ
PDIRAAFQDNKADELRIVVSSPVATIKIEVSPVARGTLHSAEIMPVQESVEDEFGYAEIQVVSLPDLYGGKLCAAMDRQH
PRDLFDVRMLLGSEGISREILVGFLTYTLSHPRPINEVMSPNWQPLNEKFQAEFDGMTFEKVECEDLAS

Download         Length: 690 bp

>T168577 NZ_CP076122:1386902-1387246 [Ralstonia solanacearum]
ATGGATGCTACCTTTATCGAGTTGCCGCCTTTTCAGAGGCTGCGGGAGCACTATCTCTCGGACGACGAGTACCGAGCGCT
CCAACAGGAACTGCTGGCCCGGCCGGACGCCGGCGACGTCATCAAGGGGACAGGTGGCCTACGCAAGCTGCGATTTTCGG
ACAAGCGGCGCGGCAAAGGTAAGCGCGGCGGTCTGCGCGTGATTGACTACCACTGGGATGGAGGCGGTCAATTCTGGATG
TTTGTCGTCTACGACAAGGGCGAGGCGGACGACCTTTCCAGCGACGAGCGCAAAGTGCTGGCACGGCTGTTGGAGCAGGA
AGTCAAGGCAAGGAGTGAGCGATGA

Antitoxin


Download         Length: 264 a.a.        Molecular weight: 30194.60 Da        Isoelectric Point: 9.6407

>AT168577 WP_181489243.1 NZ_CP059298:652713-653504 [Providencia rettgeri]
MSSKINWLVAHTSPGALVLQQWLTENGVSYSLAQKYTQNGWLKKLSSGVYYRPNAQGDIKPTWVDAIQALDVQLGVPVHL
AGLSSLTHQGLSHYLQLNKEQVWICVKNKSSLPKWFREFPYQNWFYCGNHKLEVNPEKDLKRIRVKEKELTVSCAELAAY
EVVDAIGKLISFEHVAELFQGLVNLSPRKVQDILERSSSVQANRIFLFLGRYYDHQWVNRIDETRIKLGAGKRQVVEKGR
FDERYQITVPEILSVKKGEQHNG

Download         Length: 792 bp

>AT168577 NZ_CP076122:1387243-1387554 [Ralstonia solanacearum]
ATGAAACGGAACCTGTTTGCTGAGTTGAAGGAGGGGATGGATGCGCTTGCCGCAGAGCGCGAAGGAAAGATGACCCTTCG
CAAGGTGAAGGTCCGCGTGCTCCAGCCGCTTGACGTGACAGCCGAAGAAATCAAGGCCGTTCGCGCAGCGGCACATGCTT
CACAGGCTGTCATGGCACGTCGACTGCGCGTCAATGTGCGCACCTACCAGAACTGGGAACAAGGAACCGCCAAACCGAAC
ACCCAGGCGGCTGTGTTGATCAAGCTCGTCGAGAAGCATCCGGAAACGTTGCAGATGCTGGAAGCGCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References