Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/COG3657-dnstrm_HI1420
Location 256585..257168 Replicon chromosome
Accession NZ_CP059298
Organism Providencia rettgeri strain P01

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag H0904_RS01220 Protein ID WP_096863599.1
Coordinates 256585..256887 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H0904_RS01225 Protein ID WP_004265229.1
Coordinates 256884..257168 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0904_RS01200 253828..254274 + 447 WP_006812851.1 phage tail protein -
H0904_RS01205 254271..255380 + 1110 WP_181489095.1 phage late control D family protein -
H0904_RS01210 255445..255663 + 219 WP_119246396.1 ogr/Delta-like zinc finger family protein -
H0904_RS01215 255698..256279 - 582 WP_181489097.1 hypothetical protein -
H0904_RS01220 256585..256887 + 303 WP_096863599.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H0904_RS01225 256884..257168 + 285 WP_004265229.1 putative addiction module antidote protein Antitoxin
H0904_RS01230 257251..257832 + 582 WP_094961882.1 HutD family protein -
H0904_RS01235 258052..258804 + 753 WP_004907010.1 M48 family metallopeptidase -
H0904_RS01240 259042..259683 + 642 WP_140172874.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
H0904_RS01245 259680..260624 + 945 WP_102140623.1 phosphatidate cytidylyltransferase -
H0904_RS01250 261031..262008 + 978 WP_004265237.1 6-phosphofructokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 224617..257168 32551


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-93)

Antitoxin

Uncharacterized protein HI1420

(3-91)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11433.37 Da        Isoelectric Point: 10.0723

>T168575 WP_096863599.1 NZ_CP059298:256585-256887 [Providencia rettgeri]
MITVLTTECFDSWIKNLRDIRAKTKILMRIRRLKNGNYGDVQPIGDGFSELRVHEGQGYRVYLKQKNNVIVILLCGGTKA
TQQKDIHKAKLLFGEVEGEL

Download         Length: 303 bp

>T168575 NZ_CP076122:c1352011-1351706 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACAGGGATGACCCGCGAAGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10454.13 Da        Isoelectric Point: 4.5983

>AT168575 WP_004265229.1 NZ_CP059298:256884-257168 [Providencia rettgeri]
MNTKLKEFDIAEYLNSEEEIQMYLNEILEEGDPSLVLAALGDIAKARNMSQLAKEVGMSREGLYKALSGQGNPTFMTIIK
IVNSLGLKLQFKSI

Download         Length: 285 bp

>AT168575 NZ_CP076122:c1352316-1352008 [Ralstonia solanacearum]
ATGCTGACGATCCGCACGACCGAAATCTTCGACGACTGGTTTTGCAGCCTCCGCGACAAGGCTGCGCAACGCCGCATCCA
GGTGCGCATCGACCGCCTGCAGATGGGCCACCCAGGCAACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCG
ATCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCG
ACGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References