Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) brnT-AbkA/BrnT-BrnA
Location 1008880..1009414 Replicon chromosome
Accession NZ_CP059297
Organism Brevundimonas sp. AJA228-03

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag HZ989_RS05005 Protein ID WP_209322531.1
Coordinates 1008880..1009179 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name AbkA Uniprot ID -
Locus tag HZ989_RS05010 Protein ID WP_245162459.1
Coordinates 1009199..1009414 (+) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZ989_RS04990 (HZ989_04995) 1004608..1006392 - 1785 WP_245162458.1 DUF4153 domain-containing protein -
HZ989_RS04995 (HZ989_05000) 1006443..1006928 - 486 WP_209322529.1 DUF1203 domain-containing protein -
HZ989_RS05000 (HZ989_05005) 1007033..1008841 + 1809 WP_209322530.1 M3 family oligoendopeptidase -
HZ989_RS05005 (HZ989_05010) 1008880..1009179 + 300 WP_209322531.1 BrnT family toxin Toxin
HZ989_RS05010 (HZ989_05015) 1009199..1009414 + 216 WP_245162459.1 BrnA antitoxin family protein Antitoxin
HZ989_RS05015 (HZ989_05020) 1009483..1009758 + 276 WP_209322533.1 aa3-type cytochrome c oxidase subunit IV -
HZ989_RS05020 (HZ989_05025) 1009923..1011062 + 1140 WP_209322534.1 Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha -
HZ989_RS05025 (HZ989_05030) 1011062..1011406 + 345 WP_209322535.1 NAD(P) transhydrogenase subunit alpha -
HZ989_RS05030 (HZ989_05035) 1011406..1011699 + 294 WP_209322536.1 hypothetical protein -
HZ989_RS05035 (HZ989_05040) 1011696..1011995 + 300 WP_209322537.1 hypothetical protein -
HZ989_RS05040 (HZ989_05045) 1011992..1012375 + 384 WP_209322538.1 hypothetical protein -
HZ989_RS05045 (HZ989_05050) 1012375..1012677 + 303 WP_209322539.1 nucleotidyltransferase domain-containing protein -
HZ989_RS05050 (HZ989_05055) 1012674..1013021 + 348 WP_209322540.1 DUF86 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-86)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(22-64)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11418.81 Da        Isoelectric Point: 5.5896

>T168570 WP_209322531.1 NZ_CP059297:1008880-1009179 [Brevundimonas sp. AJA228-03]
MKFDWDDAKARSNLAKHGIAFDWAIHVFEDPDAISGMDRVVDGEMRWRTVGRVGFTTILFVGHTWVDEDGEIYVRVITAR
KASRHEIKGYETGDERYLS

Download         Length: 300 bp

>T168570 NZ_CP076117:c1242082-1241336 [Bacillus amyloliquefaciens]
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTGAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCTGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCAGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8158.21 Da        Isoelectric Point: 5.0336

>AT168570 WP_245162459.1 NZ_CP059297:1009199-1009414 [Brevundimonas sp. AJA228-03]
MTDEDIDFSDAPEITDFSGFKRGLFYRPEKQAVTIRLDADVVAWFKSAEPKYQTAVNRVLREYMLAHTKAG

Download         Length: 216 bp

>AT168570 NZ_CP076117:c1241335-1241165 [Bacillus amyloliquefaciens]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References