Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3362993..3363138 Replicon chromosome
Accession NZ_CP059295
Organism Klebsiella pneumoniae strain ER17974.3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3363029..3363131 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3362993..3363138 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0490_RS15875 3358123..3360183 + 2061 WP_004151449.1 oligopeptidase B -
H0490_RS15880 3360187..3360846 - 660 WP_002911407.1 exodeoxyribonuclease X -
H0490_RS15885 3360925..3361155 - 231 WP_002911406.1 DNA polymerase III subunit theta -
H0490_RS15890 3361268..3361642 + 375 WP_004151448.1 CopC domain-containing protein YobA -
H0490_RS15895 3361646..3362515 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
H0490_RS15900 3362532..3362870 + 339 WP_002911404.1 YebY family protein -
- 3362993..3363138 - 146 - - Antitoxin
- 3363029..3363131 + 103 - - Toxin
H0490_RS15905 3363506..3363649 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
H0490_RS15910 3363754..3364722 - 969 WP_004151446.1 VirK/YbjX family protein -
H0490_RS15915 3364879..3365532 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
H0490_RS15920 3365529..3365720 - 192 WP_002911395.1 YebW family protein -
H0490_RS15925 3365818..3366057 - 240 WP_002911393.1 YebV family protein -
H0490_RS15930 3366173..3367606 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T168554 NZ_CP059295:3363029-3363131 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT168554 NZ_CP059295:c3363138-3362993 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References