Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1981461..1981699 Replicon chromosome
Accession NZ_CP059288
Organism Escherichia coli strain 1506

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1981591..1981694 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1981461..1981699 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0481_RS09540 1978016..1978678 - 663 WP_181464077.1 exodeoxyribonuclease X -
H0481_RS09545 1978702..1979358 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H0481_RS09550 1979460..1979690 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H0481_RS09555 1979829..1980203 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H0481_RS09560 1980207..1981079 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
H0481_RS09565 1981092..1981433 + 342 WP_000976472.1 YebY family protein -
- 1981461..1981699 - 239 - - Antitoxin
- 1981591..1981694 + 104 - - Toxin
H0481_RS09570 1981772..1982857 - 1086 WP_019076535.1 phage integrase Arm DNA-binding domain-containing protein -
H0481_RS09575 1982826..1983098 - 273 WP_003841650.1 excisionase -
H0481_RS09580 1983163..1983405 - 243 WP_115735511.1 DUF4060 family protein -
H0481_RS09585 1983445..1984485 - 1041 WP_115735512.1 recombinase RecT -
H0481_RS09590 1984500..1984622 - 123 Protein_1870 exodeoxyribonuclease VIII -
H0481_RS09595 1984679..1985376 + 698 Protein_1871 IS1 family transposase -
H0481_RS09600 1985311..1985577 - 267 WP_181464078.1 hypothetical protein -
H0481_RS09605 1985599..1986216 + 618 WP_113418152.1 hypothetical protein -
H0481_RS09610 1986213..1986593 + 381 WP_000637185.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1975959..1997744 21785
- flank IS/Tn - - 1984873..1985376 503


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T168530 NZ_CP059288:1981591-1981694 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 239 bp

>AT168530 NZ_CP059288:c1981699-1981461 [Escherichia coli]
CACATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGT
CAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References