Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1966732..1967003 Replicon chromosome
Accession NZ_CP059283
Organism Escherichia coli strain SY3626_hybrid

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1966862..1966965 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1966732..1967003 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0155_RS09595 1963287..1963949 - 663 WP_000944258.1 exodeoxyribonuclease X -
H0155_RS09600 1963973..1964629 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H0155_RS09605 1964731..1964961 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H0155_RS09610 1965100..1965474 + 375 WP_023281675.1 CopC domain-containing protein YobA -
H0155_RS09615 1965478..1966350 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
H0155_RS09620 1966363..1966704 + 342 WP_000976472.1 YebY family protein -
- 1966732..1967003 - 272 - - Antitoxin
- 1966862..1966965 + 104 - - Toxin
H0155_RS09625 1967100..1967756 + 657 WP_176580606.1 protein-serine/threonine phosphatase -
H0155_RS09630 1967757..1967948 - 192 WP_001338167.1 YebW family protein -
H0155_RS09635 1968053..1968289 - 237 WP_001338166.1 DUF1480 family protein -
H0155_RS09640 1968407..1969846 - 1440 WP_001397399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T168499 NZ_CP059283:1966862-1966965 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT168499 NZ_CP059283:c1967003-1966732 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References