Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2537959..2538230 Replicon chromosome
Accession NZ_CP059125
Organism Escherichia coli strain EC45

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2537997..2538100 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2537959..2538230 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0X93_RS12260 2535116..2536555 + 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
H0X93_RS12265 2536673..2536909 + 237 WP_001295499.1 YebV family protein -
H0X93_RS12270 2537014..2537205 + 192 WP_001296140.1 YebW family protein -
H0X93_RS12275 2537206..2537862 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2537959..2538230 + 272 - - Antitoxin
- 2537997..2538100 - 104 - - Toxin
H0X93_RS12280 2538258..2538599 - 342 WP_000976492.1 YebY family protein -
H0X93_RS12285 2538612..2539484 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
H0X93_RS12290 2539488..2539862 - 375 WP_000204699.1 CopC domain-containing protein YobA -
H0X93_RS12295 2540001..2540231 + 231 WP_000916763.1 DNA polymerase III subunit theta -
H0X93_RS12300 2540333..2540989 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
H0X93_RS12305 2541013..2541675 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T168302 NZ_CP059125:c2538100-2537997 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT168302 NZ_CP059125:2537959-2538230 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References