Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 539131..540041 Replicon plasmid pAR1aA
Accession NZ_CP059091
Organism Pantoea agglomerans strain AR1a

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag H0Z11_RS23550 Protein ID WP_069026891.1
Coordinates 539571..540041 (+) Length 157 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag H0Z11_RS23545 Protein ID WP_064703869.1
Coordinates 539131..539574 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0Z11_RS23515 (H0Z11_23510) 534200..535048 - 849 WP_022624593.1 transporter substrate-binding domain-containing protein -
H0Z11_RS23520 (H0Z11_23515) 535070..536257 - 1188 WP_207092154.1 M20 family metallopeptidase -
H0Z11_RS23525 (H0Z11_23520) 536499..537398 - 900 WP_208003392.1 alpha/beta hydrolase -
H0Z11_RS23530 (H0Z11_23525) 537449..538063 - 615 WP_208003393.1 TetR/AcrR family transcriptional regulator -
H0Z11_RS23535 (H0Z11_23530) 538277..538694 + 418 Protein_515 LysR substrate-binding domain-containing protein -
H0Z11_RS23540 (H0Z11_23535) 538729..538986 - 258 Protein_516 aldo/keto reductase -
H0Z11_RS23545 (H0Z11_23540) 539131..539574 + 444 WP_064703869.1 DUF2384 domain-containing protein Antitoxin
H0Z11_RS23550 (H0Z11_23545) 539571..540041 + 471 WP_069026891.1 RES family NAD+ phosphorylase Toxin
H0Z11_RS23555 (H0Z11_23550) 540213..541244 + 1032 WP_010670602.1 AI-2E family transporter -
H0Z11_RS23560 (H0Z11_23555) 541233..543962 - 2730 WP_208003394.1 cation-transporting P-type ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..557771 557771


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre

(16-147)


Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 17466.90 Da        Isoelectric Point: 4.7699

>T168260 WP_069026891.1 NZ_CP059091:539571-540041 [Pantoea agglomerans]
MILYRLTKTKYLSTAWTGFGAKEAGGRWNSIGISMVYVSETASLTLLETLVHLHSAHILDAFTLLRIDVPDALIQTADIT
ELPANWADEDAPAELADYGDAWCSACDAVALRVPSALSPVEYNYLLNPEHPDFFRIVQQAEAIPFRFDRRLKPDRK

Download         Length: 471 bp

>T168260 NZ_CP075687:c5461-5189 [Pseudomonas amygdali pv. lachrymans]
GTGCTAGTTGAGTGGCTTCCACAAGCTTTGGAGGCACTGGAGGAAATCGCCGGCTACCTAGCCGAGCGCAACCCTTATGC
TGCCGAGCAGATGCAGGCCACCCTTGAGGCCACGGTCGAGGCTCTCCCCCTGCACCCTTACATCCACCGTCCCGGCCGTG
TTCCAGGAACGCGCGAAGCGGTTGTGCATCCCAACTACCTGGTTGTCTACCGCGTCGGTACAGAGCGCATCAGCATCTTG
GACGTCCTGCACGCCCGCCAAGAGTACCCCTAG

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16463.84 Da        Isoelectric Point: 9.9250

>AT168260 WP_064703869.1 NZ_CP059091:539131-539574 [Pantoea agglomerans]
MKTFSFSANKTRAPRLWQAAGLNNADGVALLGQINEGLDGNVAHLIVNWAKITQNDLRKMSGIPSTTFSRSVKAKFSAEQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKMPAELMASETGAYEVMKLITRLEHGVYS

Download         Length: 444 bp

>AT168260 NZ_CP075687:c5636-5451 [Pseudomonas amygdali pv. lachrymans]
ATGAGCATTCAACTTGACCCTCGCGTCTCGGAGTTCGAGACCCAGGAACAGGCCGACAATTACGACCGTTGGTTTCGCCA
GCGTATCGAGCGCAGTTTGGCCGATCCGCGTCCACCCGTGCCGCACGATGAAGCAATGGCCCGCGTCAGAGCCATGATAG
AGGCAAAGCGCCGCCGTGCTAGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References