Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeV-yafW/CbtA-CbeA
Location 3627069..3627750 Replicon chromosome
Accession NZ_CP059089
Organism Pantoea agglomerans strain AR1a

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag H0Z11_RS18080 Protein ID WP_208002468.1
Coordinates 3627069..3627389 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yafW Uniprot ID -
Locus tag H0Z11_RS18085 Protein ID WP_208003204.1
Coordinates 3627457..3627750 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0Z11_RS18040 (H0Z11_18030) 3622106..3622372 - 267 WP_208003201.1 DUF2778 domain-containing protein -
H0Z11_RS18045 (H0Z11_18035) 3622369..3622698 - 330 WP_137241118.1 endoribonuclease SymE -
H0Z11_RS18050 (H0Z11_18040) 3623221..3623544 - 324 Protein_3299 DNA-binding transcriptional regulator -
H0Z11_RS18055 (H0Z11_18045) 3623528..3623782 - 255 Protein_3300 type II toxin-antitoxin system RelE/ParE family toxin -
H0Z11_RS18060 (H0Z11_18050) 3623977..3625029 + 1053 WP_208002466.1 hypothetical protein -
H0Z11_RS18065 (H0Z11_18055) 3625023..3625298 + 276 WP_033759756.1 hypothetical protein -
H0Z11_RS18070 (H0Z11_18060) 3625483..3625716 + 234 WP_208003203.1 MarR family transcriptional regulator -
H0Z11_RS18075 (H0Z11_18065) 3626122..3626955 - 834 WP_208002467.1 DUF4942 domain-containing protein -
H0Z11_RS18080 (H0Z11_18070) 3627069..3627389 - 321 WP_208002468.1 TA system toxin CbtA family protein Toxin
H0Z11_RS18085 (H0Z11_18075) 3627457..3627750 - 294 WP_208003204.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
H0Z11_RS18090 (H0Z11_18080) 3627807..3628283 - 477 WP_208002469.1 RadC family protein -
H0Z11_RS18095 (H0Z11_18085) 3628299..3628778 - 480 WP_034493134.1 antirestriction protein -
H0Z11_RS18100 (H0Z11_18090) 3629416..3630465 + 1050 WP_208002470.1 lysogenic conversion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3618270..3657919 39649


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-105)

Antitoxin

Antitoxin CbeA

(1-92)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12082.79 Da        Isoelectric Point: 5.0497

>T168255 WP_208002468.1 NZ_CP059089:c3627389-3627069 [Pantoea agglomerans]
MQISTVPATLPVSSRLSPVQVWQQLLTYLLEQHYGMTLNETPLHEDAAIQEHIEAGITLADALNFLVERYELVRTDRKGF
TWQEQTPFLTATDILRARRATGLMNT

Download         Length: 321 bp

>T168255 NZ_CP075681:c1242124-1241378 [Bacillus velezensis]
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTGAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCTGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCAGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10797.23 Da        Isoelectric Point: 5.8689

>AT168255 WP_208003204.1 NZ_CP059089:c3627750-3627457 [Pantoea agglomerans]
ITPCFGARLVQEGHRLHFLADRAGFNGSFSEMQARDLDEAFPHFVAHMELMLLSGELNLRCGHCVTLYRNGLTCEADTLG
SHGDVYIAIYPSNQVKD

Download         Length: 294 bp

>AT168255 NZ_CP075681:c1241377-1241207 [Bacillus velezensis]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References