Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 32685..33211 Replicon plasmid pAR1aB
Accession NZ_CP059088
Organism Pantoea agglomerans strain AR1a

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag H0Z11_RS00600 Protein ID WP_115764660.1
Coordinates 32685..32972 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H0Z11_RS00605 Protein ID WP_083070603.1
Coordinates 32972..33211 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0Z11_RS00575 (H0Z11_00575) 28585..29610 - 1026 WP_207874179.1 alpha/beta hydrolase -
H0Z11_RS00580 (H0Z11_00580) 29679..30803 - 1125 WP_241866617.1 MFS transporter -
H0Z11_RS00585 (H0Z11_00585) 31006..31905 + 900 WP_031593077.1 LysR family transcriptional regulator -
H0Z11_RS00590 (H0Z11_00590) 31966..32142 - 177 WP_010257023.1 KGG domain-containing protein -
H0Z11_RS00595 (H0Z11_00595) 32344..32640 + 297 WP_207874183.1 hypothetical protein -
H0Z11_RS00600 (H0Z11_00600) 32685..32972 - 288 WP_115764660.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H0Z11_RS00605 (H0Z11_00605) 32972..33211 - 240 WP_083070603.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
H0Z11_RS00610 (H0Z11_00610) 33552..35525 + 1974 Protein_31 methyl-accepting chemotaxis protein -
H0Z11_RS00615 (H0Z11_00615) 35630..36646 + 1017 WP_039387390.1 NAD(P)-dependent alcohol dehydrogenase -
H0Z11_RS00620 (H0Z11_00620) 36696..37364 - 669 WP_241866616.1 DUF2268 domain-containing putative Zn-dependent protease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..160336 160336


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-78)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11031.88 Da        Isoelectric Point: 10.2573

>T168247 WP_115764660.1 NZ_CP059088:c32972-32685 [Pantoea agglomerans]
MPWQLECDQRALKEWRKLGPTVREQLKKKLAECLESPRIEANKLSRMPDCYKIKLKSSGYRLAYQVIDDRVVVFVVAVGK
RERSEVNSAASRHLS

Download         Length: 288 bp

>T168247 NZ_CP075666:26256-26561 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTCCAGAGTGACATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCCCGCCTGCTGTCAGATAAAGTCTCCCGTGAACTTTACCCGGTGG
TGCATGTCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGCCACCGGGAAAATGACATCAAAAATGCCATTAACCTGATGTTCTGGGGAATATAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8910.35 Da        Isoelectric Point: 8.6146

>AT168247 WP_083070603.1 NZ_CP059088:c33211-32972 [Pantoea agglomerans]
VGSISIRIDDDLKRRSFAALKKMGVTPSDALRLMLAYIADNERLPFKQTSLSDEDAALVDIVKERLRNPEPVRITLDKL

Download         Length: 240 bp

>AT168247 NZ_CP075666:26036-26254 [Escherichia coli]
ATGAAGCAGCGTATTACAGTGACAGTTGACAGCGACAGCTATCAGCTGCTCAAGGCGTATGACGTGAATATCTCCGGTCT
GGTCAGTACGACCATGCAGAACGAAGCCCGGCGACTGCGTGCTGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCAG
AGGTCGCCAGGTTTATTGAAATGAATGGCTCTTTTGCCGATGAGAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References